Catalytic Asymmetric Formal Total Synthesis of (-)-Triptophenolide and (+)-Triptolide.

	Catalytic Asymmetric Formal Total Synthesis of (-)-Triptophenolide and (+)-Triptolide.
	Xu, Wen-Dan; Li, Liang-Qun; Li, Ming-Ming; Geng, Hui-Chun; Qin, Hong-Bo
	2016
发表期刊	Natural products and bioprospecting
ISSN	2192-2195
卷号	6 期号:3 页码:183-6
摘要	Catalytic asymmetric formal synthesis of (-)-Triptophenolide and (+)-Triptolide have been achieved. Key reaction involves Palladium catalyzed asymmetric conjugate addition of aryl boronic acid to 3-methyl cyclohexe-1-none to form quaternary carbon. Claisen rearrangement and subsequent aldol reaction furnished trans-decaline key intermediate, which assured a formal total synthesis of (-)-Triptophenolide and (+)-Triptolide.
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/64890
专题	植物化学与西部植物资源持续利用国家重点实验室
推荐引用方式 GB/T 7714	Xu, Wen-Dan,Li, Liang-Qun,Li, Ming-Ming,et al. Catalytic Asymmetric Formal Total Synthesis of (-)-Triptophenolide and (+)-Triptolide.[J]. Natural products and bioprospecting,2016,6(3):183-6.
APA	Xu, Wen-Dan,Li, Liang-Qun,Li, Ming-Ming,Geng, Hui-Chun,&Qin, Hong-Bo.(2016).Catalytic Asymmetric Formal Total Synthesis of (-)-Triptophenolide and (+)-Triptolide..Natural products and bioprospecting,6(3),183-6.
MLA	Xu, Wen-Dan,et al."Catalytic Asymmetric Formal Total Synthesis of (-)-Triptophenolide and (+)-Triptolide.".Natural products and bioprospecting 6.3(2016):183-6.