| New Cytotoxic Cycloartane Triterpenes from the Aerial Parts of Actaea heracleifolia (syn. Cimicifuga heracleifolia) | |
Shi, Qiang-Qiang1,2,3; Wang, Wei-Hua1,2,3; Lu, Jing1,2,3; Li, Da-Shan1,3; Zhou, Lin1,3; Qiu, Ming-Hua1,3
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| 2019 | |
| Source Publication | PLANTA MEDICA
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| ISSN | 0032-0943 |
| Volume | 85Issue:2Pages:154-159 |
| Abstract | One new 15,16-seco-cycloartane triterpene (1), three new cycloartane triterpene glycosides (2-4), and five known compounds (5-9) were isolated from the aerial parts of Actaea heracleifolia. The chemical structures of these compounds were determined on the basis of NMR analysis, HRTOF-ESIMS data, and other spectroscopic methods. Selected compounds were evaluated for their cytotoxicity against human tumor cell lines (HL-60, SMMC-7721, A549, MCF-7, and SW480) in vitro. Compounds 3 and 4 showed weak activity against the HL-60, A-549, and MCF-7 cell lines with IC50 values ranging from 21.34 to 36.98 mu M. |
| Keyword | Actaea heracleifolia Ranunculaceae 15 16-seco-cycloartane triterpene cycloartane triterpene glycosides cytotoxicity NMR |
| Indexed By | SCI |
| Language | 英语 |
| Document Type | 期刊论文 |
| Identifier | http://ir.kib.ac.cn/handle/151853/64633 |
| Collection | 植物化学与西部植物资源持续利用国家重点实验室 |
| Corresponding Author | Qiu, Ming-Hua |
| Affiliation | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, 132 Lanhei Rd, Kunming 650201, Yunnan, Peoples R China 2.Univ Chinese Acad Sci, Beijing, Peoples R China 3.Chinese Acad Sci, Yunnan Key Lab Nat Med Chem, Kunming, Yunnan, Peoples R China |
| Recommended Citation GB/T 7714 | Shi, Qiang-Qiang,Wang, Wei-Hua,Lu, Jing,et al. New Cytotoxic Cycloartane Triterpenes from the Aerial Parts of Actaea heracleifolia (syn. Cimicifuga heracleifolia)[J]. PLANTA MEDICA,2019,85(2):154-159. |
| APA | Shi, Qiang-Qiang,Wang, Wei-Hua,Lu, Jing,Li, Da-Shan,Zhou, Lin,&Qiu, Ming-Hua.(2019).New Cytotoxic Cycloartane Triterpenes from the Aerial Parts of Actaea heracleifolia (syn. Cimicifuga heracleifolia).PLANTA MEDICA,85(2),154-159. |
| MLA | Shi, Qiang-Qiang,et al."New Cytotoxic Cycloartane Triterpenes from the Aerial Parts of Actaea heracleifolia (syn. Cimicifuga heracleifolia)".PLANTA MEDICA 85.2(2019):154-159. |
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| Shi-2019-New Cytotox（173KB） | 期刊论文 | 出版稿 | 开放获取 | CC BY-NC-SA | View Download | |
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