New Cytotoxic Cycloartane Triterpenes from the Aerial Parts of Actaea heracleifolia (syn. Cimicifuga heracleifolia)
Shi, Qiang-Qiang1,2,3; Wang, Wei-Hua1,2,3; Lu, Jing1,2,3; Li, Da-Shan1,3; Zhou, Lin1,3; Qiu, Ming-Hua1,3
2019
Source PublicationPLANTA MEDICA
ISSN0032-0943
Volume85Issue:2Pages:154-159
AbstractOne new 15,16-seco-cycloartane triterpene (1), three new cycloartane triterpene glycosides (2-4), and five known compounds (5-9) were isolated from the aerial parts of Actaea heracleifolia. The chemical structures of these compounds were determined on the basis of NMR analysis, HRTOF-ESIMS data, and other spectroscopic methods. Selected compounds were evaluated for their cytotoxicity against human tumor cell lines (HL-60, SMMC-7721, A549, MCF-7, and SW480) in vitro. Compounds 3 and 4 showed weak activity against the HL-60, A-549, and MCF-7 cell lines with IC50 values ranging from 21.34 to 36.98 mu M.
KeywordActaea heracleifolia Ranunculaceae 15 16-seco-cycloartane triterpene cycloartane triterpene glycosides cytotoxicity NMR
Indexed BySCI
Language英语
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/64633
Collection植物化学与西部植物资源持续利用国家重点实验室
Corresponding AuthorQiu, Ming-Hua
Affiliation1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, 132 Lanhei Rd, Kunming 650201, Yunnan, Peoples R China
2.Univ Chinese Acad Sci, Beijing, Peoples R China
3.Chinese Acad Sci, Yunnan Key Lab Nat Med Chem, Kunming, Yunnan, Peoples R China
Recommended Citation
GB/T 7714
Shi, Qiang-Qiang,Wang, Wei-Hua,Lu, Jing,et al. New Cytotoxic Cycloartane Triterpenes from the Aerial Parts of Actaea heracleifolia (syn. Cimicifuga heracleifolia)[J]. PLANTA MEDICA,2019,85(2):154-159.
APA Shi, Qiang-Qiang,Wang, Wei-Hua,Lu, Jing,Li, Da-Shan,Zhou, Lin,&Qiu, Ming-Hua.(2019).New Cytotoxic Cycloartane Triterpenes from the Aerial Parts of Actaea heracleifolia (syn. Cimicifuga heracleifolia).PLANTA MEDICA,85(2),154-159.
MLA Shi, Qiang-Qiang,et al."New Cytotoxic Cycloartane Triterpenes from the Aerial Parts of Actaea heracleifolia (syn. Cimicifuga heracleifolia)".PLANTA MEDICA 85.2(2019):154-159.
Files in This Item:
There are no files associated with this item.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Shi, Qiang-Qiang]'s Articles
[Wang, Wei-Hua]'s Articles
[Lu, Jing]'s Articles
Baidu academic
Similar articles in Baidu academic
[Shi, Qiang-Qiang]'s Articles
[Wang, Wei-Hua]'s Articles
[Lu, Jing]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Shi, Qiang-Qiang]'s Articles
[Wang, Wei-Hua]'s Articles
[Lu, Jing]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.