Cytochalasans from the Endophytic Fungus Xylaria cf. curta with Resistance Reversal Activity against Fluconazole-Resistant Candida albicans

	Cytochalasans from the Endophytic Fungus Xylaria cf. curta with Resistance Reversal Activity against Fluconazole-Resistant Candida albicans
	Wang, Wen-Xuan 1; Lei, Xinxiang 1; Ai, Hong-Lian 1; Bai, Xue 2; Li, Jing1 ; He, Juan 1; Li, Zheng-Hui 1; Zheng, Yong-Sheng 1; Feng, Tao 1; Liu, Ji-Kai 1
	2019-02-15
发表期刊	ORGANIC LETTERS
ISSN	1523-7060
卷号	21 期号:4 页码:1108-1111
摘要	Curtachalasins C-E (1-3), which have an unprecedent bridged 6/6/6/6 ring system, were identified from the endophytic fungus Xylaria cf. curta. Residual dipolar coupling analyses associating with density functional theory calculations were utilized to determine the relative configuration of noncrystallizable compound 2. The absolute configurations of 1-3 were determined by X-ray diffraction and electronic circular dichroism calculations. Remarkably, curtachalasin C (1) showed significant resistance reversal activity against fluconazole-resistant Candida albicans.
收录类别	SCI
语种	英语
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/64599
专题	植物化学与西部植物资源持续利用国家重点实验室
通讯作者	Ai, Hong-Lian; Feng, Tao; Liu, Ji-Kai
作者单位	1.South Cent Univ Nationalities, Sch Pharmaceut Sci, Wuhan 430074, Hubei, Peoples R China 2.Chinese Acad Sci, Kunming Inst Bot, Kunming 650204, Yunnan, Peoples R China
推荐引用方式 GB/T 7714	Wang, Wen-Xuan,Lei, Xinxiang,Ai, Hong-Lian,et al. Cytochalasans from the Endophytic Fungus Xylaria cf. curta with Resistance Reversal Activity against Fluconazole-Resistant Candida albicans[J]. ORGANIC LETTERS,2019,21(4):1108-1111.
APA	Wang, Wen-Xuan.,Lei, Xinxiang.,Ai, Hong-Lian.,Bai, Xue.,Li, Jing.,...&Liu, Ji-Kai.(2019).Cytochalasans from the Endophytic Fungus Xylaria cf. curta with Resistance Reversal Activity against Fluconazole-Resistant Candida albicans.ORGANIC LETTERS,21(4),1108-1111.
MLA	Wang, Wen-Xuan,et al."Cytochalasans from the Endophytic Fungus Xylaria cf. curta with Resistance Reversal Activity against Fluconazole-Resistant Candida albicans".ORGANIC LETTERS 21.4(2019):1108-1111.

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