| Cytochalasans from the Endophytic Fungus Xylaria cf. curta with Resistance Reversal Activity against Fluconazole-Resistant Candida albicans | |
Wang, Wen-Xuan1; Lei, Xinxiang1; Ai, Hong-Lian1; Bai, Xue2; Li, Jing1 ; He, Juan1; Li, Zheng-Hui1; Zheng, Yong-Sheng1; Feng, Tao1; Liu, Ji-Kai1
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| 2019-02-15 | |
| 发表期刊 | ORGANIC LETTERS
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| ISSN | 1523-7060 |
| 卷号 | 21期号:4页码:1108-1111 |
| 摘要 | Curtachalasins C-E (1-3), which have an unprecedent bridged 6/6/6/6 ring system, were identified from the endophytic fungus Xylaria cf. curta. Residual dipolar coupling analyses associating with density functional theory calculations were utilized to determine the relative configuration of noncrystallizable compound 2. The absolute configurations of 1-3 were determined by X-ray diffraction and electronic circular dichroism calculations. Remarkably, curtachalasin C (1) showed significant resistance reversal activity against fluconazole-resistant Candida albicans. |
| 收录类别 | SCI |
| 语种 | 英语 |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kib.ac.cn/handle/151853/64599 |
| 专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
| 通讯作者 | Ai, Hong-Lian; Feng, Tao; Liu, Ji-Kai |
| 作者单位 | 1.South Cent Univ Nationalities, Sch Pharmaceut Sci, Wuhan 430074, Hubei, Peoples R China 2.Chinese Acad Sci, Kunming Inst Bot, Kunming 650204, Yunnan, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Wen-Xuan,Lei, Xinxiang,Ai, Hong-Lian,et al. Cytochalasans from the Endophytic Fungus Xylaria cf. curta with Resistance Reversal Activity against Fluconazole-Resistant Candida albicans[J]. ORGANIC LETTERS,2019,21(4):1108-1111. |
| APA | Wang, Wen-Xuan.,Lei, Xinxiang.,Ai, Hong-Lian.,Bai, Xue.,Li, Jing.,...&Liu, Ji-Kai.(2019).Cytochalasans from the Endophytic Fungus Xylaria cf. curta with Resistance Reversal Activity against Fluconazole-Resistant Candida albicans.ORGANIC LETTERS,21(4),1108-1111. |
| MLA | Wang, Wen-Xuan,et al."Cytochalasans from the Endophytic Fungus Xylaria cf. curta with Resistance Reversal Activity against Fluconazole-Resistant Candida albicans".ORGANIC LETTERS 21.4(2019):1108-1111. |
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