Cytochalasans from the Endophytic Fungus Xylaria cf. curta with Resistance Reversal Activity against Fluconazole-Resistant Candida albicans
Wang, Wen-Xuan1; Lei, Xinxiang1; Ai, Hong-Lian1; Bai, Xue2; Li, Jing1; He, Juan1; Li, Zheng-Hui1; Zheng, Yong-Sheng1; Feng, Tao1; Liu, Ji-Kai1
2019-02-15
发表期刊ORGANIC LETTERS
ISSN1523-7060
卷号21期号:4页码:1108-1111
摘要Curtachalasins C-E (1-3), which have an unprecedent bridged 6/6/6/6 ring system, were identified from the endophytic fungus Xylaria cf. curta. Residual dipolar coupling analyses associating with density functional theory calculations were utilized to determine the relative configuration of noncrystallizable compound 2. The absolute configurations of 1-3 were determined by X-ray diffraction and electronic circular dichroism calculations. Remarkably, curtachalasin C (1) showed significant resistance reversal activity against fluconazole-resistant Candida albicans.
收录类别SCI
语种英语
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/64599
专题植物化学与西部植物资源持续利用国家重点实验室
通讯作者Ai, Hong-Lian; Feng, Tao; Liu, Ji-Kai
作者单位1.South Cent Univ Nationalities, Sch Pharmaceut Sci, Wuhan 430074, Hubei, Peoples R China
2.Chinese Acad Sci, Kunming Inst Bot, Kunming 650204, Yunnan, Peoples R China
推荐引用方式
GB/T 7714
Wang, Wen-Xuan,Lei, Xinxiang,Ai, Hong-Lian,et al. Cytochalasans from the Endophytic Fungus Xylaria cf. curta with Resistance Reversal Activity against Fluconazole-Resistant Candida albicans[J]. ORGANIC LETTERS,2019,21(4):1108-1111.
APA Wang, Wen-Xuan.,Lei, Xinxiang.,Ai, Hong-Lian.,Bai, Xue.,Li, Jing.,...&Liu, Ji-Kai.(2019).Cytochalasans from the Endophytic Fungus Xylaria cf. curta with Resistance Reversal Activity against Fluconazole-Resistant Candida albicans.ORGANIC LETTERS,21(4),1108-1111.
MLA Wang, Wen-Xuan,et al."Cytochalasans from the Endophytic Fungus Xylaria cf. curta with Resistance Reversal Activity against Fluconazole-Resistant Candida albicans".ORGANIC LETTERS 21.4(2019):1108-1111.
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