Chemical constituents from the twigs and leaves of Trichilia sinensis and their biological activities

	Chemical constituents from the twigs and leaves of Trichilia sinensis and their biological activities
	Cao, Dong-Hua 1,2; Sun, Peng 1,2; Liao, Shang-Gao 3,4; Gan, Li-She 5; Yang, Lin 1; Yao, Jian-Neng 2,6; Zhang, Zong-Yi 1,2; Li, Jin-Feng 1,2; Zheng, Xiao-Ling 1,2; Xiao, Yi-Dian 6,7; Xiao, Chun-Fen 1; Zhang, Ping 1; Hu, Hua-Bin 1; Xu, You-Kai 1
	2019-02-01
发表期刊	PHYTOCHEMISTRY LETTERS
ISSN	1874-3900
卷号	29 页码:142-147
摘要	Phytochemical investigation on the twigs and leaves of Trichilia sinensis led to the isolation of two previously undescribed limonoids (i.e., trichiliasinenoids D and E, 1 and 2), two previously undescribed phenolic acids (3 and 4), and one previously undescribed natural phenolic acid dimer (5), together with 11 known compounds (616). Their structures were elucidated by extensive spectroscopic analysis (IR, UV, HRESIMS, 1D and 2D NMR) and chemical techniques. The potential anti-inflammatory activities of all the compounds were evaluated in lipopolysaccharide-stimulated RAW 264.7 cells. Among these isolates, compounds 1, 2, 6, and 11-13 expressed weak NO inhibition. The antibacterial activities of all the compounds against bacteria were also tested in vitro. Compound 16 exhibited moderate antibacterial activities against Escherichia Coli.
关键词	Trichina sinensis Meliaceae Mexicanolide-type limonoid Phenolic acid Anti-inflammatory activity Antibacterial activity
收录类别	SCI
语种	英语
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/64263
专题	植物化学与西部植物资源持续利用国家重点实验室
通讯作者	Xu, You-Kai
作者单位	1.Chinese Acad Sci, CAS Key Lab Trop Plant Resources & Sustainable Us, Xishuangbanna Trop Bot Garden, Menglun 666303, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Guizhou Med Univ, State Key Lab Funct & Applicat Med Plants, Guiyang 550025, Guizhou, Peoples R China 4.Guizhou Med Univ, Sch Pharm, Guiyang 550025, Guizhou, Peoples R China 5.Zhejiang Univ, Coll Pharmaceut Sci, Inst Modern Chinese Med, Hangzhou 310058, Zhejiang, Peoples R China 6.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 7.Yunnan Univ, Sch Chem Sci & Technol, Key Lab Med Chem Nat Resource, Minist Educ, Kunming 650091, Yunnan, Peoples R China
推荐引用方式 GB/T 7714	Cao, Dong-Hua,Sun, Peng,Liao, Shang-Gao,et al. Chemical constituents from the twigs and leaves of Trichilia sinensis and their biological activities[J]. PHYTOCHEMISTRY LETTERS,2019,29:142-147.
APA	Cao, Dong-Hua.,Sun, Peng.,Liao, Shang-Gao.,Gan, Li-She.,Yang, Lin.,...&Xu, You-Kai.(2019).Chemical constituents from the twigs and leaves of Trichilia sinensis and their biological activities.PHYTOCHEMISTRY LETTERS,29,142-147.
MLA	Cao, Dong-Hua,et al."Chemical constituents from the twigs and leaves of Trichilia sinensis and their biological activities".PHYTOCHEMISTRY LETTERS 29(2019):142-147.

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