Carpescernolides A and B, rare oxygen bridge-containing sesquiterpene lactones from Carpesium cernuum

	Carpescernolides A and B, rare oxygen bridge-containing sesquiterpene lactones from Carpesium cernuum
	Yan, Chen 1; Zhang, Wei-Qing 1; Sun, Mao 1; Liang, Wei 1; Wang, Tian-Yuan 1; Zhang, Yun-Dong 1; Ding, Xiao 2
	2018-11-14
发表期刊	TETRAHEDRON LETTERS
ISSN	0040-4039
卷号	59 期号:46 页码:4063-4066
摘要	Two new highly oxygenated germacranolides, Carpescernolides A (1) and B (2), were isolated from the whole plant of Carpesium cernuum. Their structures were established by extensive analysis of NMR spectra, as well as HRESIMS data. X-ray diffraction studies were used to confirm the absolute configurations of 1 and 2. Notably, compound 1, with an oxygen bridge unit (C-2-O-C-5) and a 4, 8-ketal system at C-8, resulted in a novel type of germacranolide compound. Compound 1 showed a moderate inhibition against SMMC-7721 cancer cells in vitro. (C) 2018 Elsevier Ltd. All rights reserved.
关键词	Carpesium cernuum Sesquiterpene SMMC-7721 cancer cells
收录类别	SCI
语种	英语
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/63174
专题	植物化学与西部植物资源持续利用国家重点实验室
通讯作者	Zhang, Yun-Dong; Ding, Xiao
作者单位	1.An Shun City Peoples Hosp, Anshun, Peoples R China 2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
推荐引用方式 GB/T 7714	Yan, Chen,Zhang, Wei-Qing,Sun, Mao,et al. Carpescernolides A and B, rare oxygen bridge-containing sesquiterpene lactones from Carpesium cernuum[J]. TETRAHEDRON LETTERS,2018,59(46):4063-4066.
APA	Yan, Chen.,Zhang, Wei-Qing.,Sun, Mao.,Liang, Wei.,Wang, Tian-Yuan.,...&Ding, Xiao.(2018).Carpescernolides A and B, rare oxygen bridge-containing sesquiterpene lactones from Carpesium cernuum.TETRAHEDRON LETTERS,59(46),4063-4066.
MLA	Yan, Chen,et al."Carpescernolides A and B, rare oxygen bridge-containing sesquiterpene lactones from Carpesium cernuum".TETRAHEDRON LETTERS 59.46(2018):4063-4066.