Iridal-type triterpenoids with anti-HBV activity from Iris confusa
Chen, Xinglong1,2; Zhang, Xiuqiong1,2; Ma, Yunbao1,2; Deng, Zhentao1,2; Geng, Changan1,2; Chen, Jijun1,2
2018-09-01
发表期刊FITOTERAPIA
ISSN0367-326X
卷号129页码:126-132
摘要Five new iridal-type triterpenoids, named as spirioiridoconfal A-C (1-3), isobelamcandal (4) and 17-hydroxyl-27-ene-iridal (5), along with one known compound (6) were isolated from the whole plant of Iris confusa. Their structures were determined by extensive spectroscopic analyses. Compounds 3 and 6 showed moderate activity against HBV DNA replication in vitro with the IC50 value at 84.6 +/- 24.9 (SI = 2.1) and 58.6 +/- 6.1 (SI = 12.7) mu M relatively.
关键词Iris confusa Iridal-type triterpenoids Anti-HBV activity
资助信息Hundred Talents Program of the Chinese Academy of Sciences; Program of Yunling Scholar of the Chinese Academy of Sciences
语种英语
资助项目Hundred Talents Program of the Chinese Academy of Sciences ; Program of Yunling Scholar of the Chinese Academy of Sciences
引用统计
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/62300
专题植物化学与西部植物资源持续利用国家重点实验室
通讯作者Chen, Jijun
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, 132 Lanhei Rd, Kunming 650201, Yunnan, Peoples R China
2.Yunnan Key Lab Nat Med Chem, Kunming 650201, Yunnan, Peoples R China
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Chen, Xinglong,Zhang, Xiuqiong,Ma, Yunbao,et al. Iridal-type triterpenoids with anti-HBV activity from Iris confusa[J]. FITOTERAPIA,2018,129:126-132.
APA Chen, Xinglong,Zhang, Xiuqiong,Ma, Yunbao,Deng, Zhentao,Geng, Changan,&Chen, Jijun.(2018).Iridal-type triterpenoids with anti-HBV activity from Iris confusa.FITOTERAPIA,129,126-132.
MLA Chen, Xinglong,et al."Iridal-type triterpenoids with anti-HBV activity from Iris confusa".FITOTERAPIA 129(2018):126-132.
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