Salweenia bouffordiana is an endangered species of Qinghai-Tibetan Plateau (QTP) in China. In this study, its complete plastome was assembled using next-generation sequencing. The complete genome is 153, 730 bp in length, comprises a pair of inverted repeat (IR; 26, 227 bp) regions separated by the large single-copy (LSC; 83, 509 bp) and small single-copy (SSC; 17, 767 bp) regions. It encodes 111 genes, including 77 protein-coding genes (PCGs), 30 tRNAs and 4 rRNAs. The nucleotide composition is asymmetric (31.6% A, 18.1% C, 18.7% G and 31.6% T) with an overall A+T content of 73.2%. Three types of 111 simple sequence repeats (SSRs) were detected in the plastome, including 107 mono- and 4 di-nucleotide repeats. The newly sequenced complete plastome and identified SSRs will help in understanding the plastome evolution and genetic conservation of S. bouffordiana.