Three New Polyynes from Codonopsis pilosula and Their Activities on Lipid Metabolism
Hu, Xiao-Yu1,2; Qin, Fu-Ying2,3; Lu, Xi-Feng2; Zhang, Lan-Sheng1; Cheng, Yong-Xian2,4,5
2018-04-01
发表期刊MOLECULES
ISSN1420-3049
卷号23期号:4
摘要Three new polyynes, named choushenpilosulynes A-C (1-3), were isolated from an 85% aqueous EtOH extract of the roots of Codonopsis pilosula cultivated in Xundian County of Yunnan province, China. Their structures, including the absolute configuration of the glucose residue in 1 and 2, were determined by spectroscopic analysis and gas chromatography (GC). In addition, biological evaluation shows that all the compounds can inhibit the expression of the squalene monooxygenase (SQLE) gene in HepG2 cells, suggesting that these compounds may be involved in lipid metabolism.
关键词Codonopsis Pilosula Choushenpilosulynes A-c Lipid Metabolism
DOI10.3390/molecules23040887
语种英语
引用统计
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/61372
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Dali Univ, Sch Pharm & Chem, Dali 671000, Peoples R China
2.Shenzhen Univ, Sch Pharmaceut Sci, Guangdong Key Lab Genome Stabil & Dis Prevent, Hlth Sci Ctr,Sch Med, Shenzhen 518060, Peoples R China
3.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
4.Henan Univ Chinese Med, Sch Pharm, Zhengzhou 450008, Henan, Peoples R China
5.Chengdu Univ Tradit Chinese Med, Coll Pharm, Chengdu 610075, Sichuan, Peoples R China
推荐引用方式
GB/T 7714
Hu, Xiao-Yu,Qin, Fu-Ying,Lu, Xi-Feng,et al. Three New Polyynes from Codonopsis pilosula and Their Activities on Lipid Metabolism[J]. MOLECULES,2018,23(4).
APA Hu, Xiao-Yu,Qin, Fu-Ying,Lu, Xi-Feng,Zhang, Lan-Sheng,&Cheng, Yong-Xian.(2018).Three New Polyynes from Codonopsis pilosula and Their Activities on Lipid Metabolism.MOLECULES,23(4).
MLA Hu, Xiao-Yu,et al."Three New Polyynes from Codonopsis pilosula and Their Activities on Lipid Metabolism".MOLECULES 23.4(2018).
条目包含的文件
条目无相关文件。
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Hu, Xiao-Yu]的文章
[Qin, Fu-Ying]的文章
[Lu, Xi-Feng]的文章
百度学术
百度学术中相似的文章
[Hu, Xiao-Yu]的文章
[Qin, Fu-Ying]的文章
[Lu, Xi-Feng]的文章
必应学术
必应学术中相似的文章
[Hu, Xiao-Yu]的文章
[Qin, Fu-Ying]的文章
[Lu, Xi-Feng]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。