NF-kappa B and JNK mediated apoptosis and G(0)/G(1) arrest of HeLa cells induced by rubiarbonol G, an arborinane-type triterpenoid from Rubia yunnanensis

doi:10.1016/j.jep.2017.10.026

	NF-kappa B and JNK mediated apoptosis and G(0)/G(1) arrest of HeLa cells induced by rubiarbonol G, an arborinane-type triterpenoid from Rubia yunnanensis
	Zeng, Guang-Zhi 3,4; Wang, Zhe1,2,3 ; Zhao, Li-Mei 3; Fan, Jun-Ting 3; Tan, Ning-Hua 1,2,3
	2018-06-28
发表期刊	JOURNAL OF ETHNOPHARMACOLOGY
ISSN	0378-8741
卷号	220 页码:220-227
摘要	Ethnopharmacological relevance: Rubia yunnanensis is a medicinal plant mainly grown in Yunnan province in Southwest China, and its root named "Xiaohongshen" has been used as a herb in Yunnan for the treatment of cancers. Three major types of chemical components, Rubiaceae-type cyclopeptides, quinones, and triterpenoids, were identified from R. yunnanensis, in which some of compounds including rubiarbonol G (RG), a unique arboriane-type triterpenoid, showed cytotoxicity on cancer cells. But the cytotoxic mechanism of RG has not been reported.
关键词	Rubiarbonol g Rubia Yunnanensis Cytotoxicity Mechanism
DOI	10.1016/j.jep.2017.10.026
语种	英语
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/61370
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.China Pharmaceut Univ, Sch Tradit Chinese Pharm, Nanjing 211198, Jiangsu, Peoples R China 2.China Pharmaceut Univ, State Key Lab Nat Med, Nanjing 211198, Jiangsu, Peoples R China 3.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 4.Yunnan Minzu Univ, YMU HKBU Joint Lab Tradit Nat Med, Kunming 650500, Yunnan, Peoples R China
推荐引用方式 GB/T 7714	Zeng, Guang-Zhi,Wang, Zhe,Zhao, Li-Mei,et al. NF-kappa B and JNK mediated apoptosis and G(0)/G(1) arrest of HeLa cells induced by rubiarbonol G, an arborinane-type triterpenoid from Rubia yunnanensis[J]. JOURNAL OF ETHNOPHARMACOLOGY,2018,220:220-227.
APA	Zeng, Guang-Zhi,Wang, Zhe,Zhao, Li-Mei,Fan, Jun-Ting,&Tan, Ning-Hua.(2018).NF-kappa B and JNK mediated apoptosis and G(0)/G(1) arrest of HeLa cells induced by rubiarbonol G, an arborinane-type triterpenoid from Rubia yunnanensis.JOURNAL OF ETHNOPHARMACOLOGY,220,220-227.
MLA	Zeng, Guang-Zhi,et al."NF-kappa B and JNK mediated apoptosis and G(0)/G(1) arrest of HeLa cells induced by rubiarbonol G, an arborinane-type triterpenoid from Rubia yunnanensis".JOURNAL OF ETHNOPHARMACOLOGY 220(2018):220-227.