Identification of new diterpene esters from green Arabica coffee beans, and their platelet aggregation accelerating activities
Wang, Xia1,2; Meng, QianQian1; Peng, XingRong1; Hu, GuiLin1,2; Qiu, MingHua1,2
2018-10-15
Source PublicationFOOD CHEMISTRY
ISSN0308-8146
Volume263Pages:251-257
AbstractEight new ent-kaurane diterpene fatty acid esters, namely caffarolides A-H (1-8), were isolated from green beans of Coffea arabica. Their chemical structures were confirmed by extensive spectroscopic analysis including 1D, 2D NMR (HSQC, HMBC, H-1-H-1 COSY, and ROESY), HRMS, IR and CD spectra and by GC-FID analysis. Interestingly, the diterpene moiety of these new compounds first occurred in genus Coffea. All the isolates were evaluated for platelet aggregation activity in vitro. As the results, caffarolides C, D and F (3, 4 and 6) showed induction effect for platelet aggregation and the possible structure-activity relationships have been discussed briefly.
KeywordCoffea Arabica Coffee Lipids Diterpene Esters Structure Elucidation Platelet Aggregation
DOI10.1016/j.foodchem.2018.04.081
Language英语
Citation statistics
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/61334
Collection植物化学与西部植物资源持续利用国家重点实验室
Affiliation1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
Recommended Citation
GB/T 7714
Wang, Xia,Meng, QianQian,Peng, XingRong,et al. Identification of new diterpene esters from green Arabica coffee beans, and their platelet aggregation accelerating activities[J]. FOOD CHEMISTRY,2018,263:251-257.
APA Wang, Xia,Meng, QianQian,Peng, XingRong,Hu, GuiLin,&Qiu, MingHua.(2018).Identification of new diterpene esters from green Arabica coffee beans, and their platelet aggregation accelerating activities.FOOD CHEMISTRY,263,251-257.
MLA Wang, Xia,et al."Identification of new diterpene esters from green Arabica coffee beans, and their platelet aggregation accelerating activities".FOOD CHEMISTRY 263(2018):251-257.
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