Identification of new diterpene esters from green Arabica coffee beans, and their platelet aggregation accelerating activities
Wang, Xia1,2; Meng, QianQian1; Peng, XingRong1; Hu, GuiLin1,2; Qiu, MingHua1,2
2018-10-15
发表期刊FOOD CHEMISTRY
ISSN0308-8146
卷号263页码:251-257
摘要Eight new ent-kaurane diterpene fatty acid esters, namely caffarolides A-H (1-8), were isolated from green beans of Coffea arabica. Their chemical structures were confirmed by extensive spectroscopic analysis including 1D, 2D NMR (HSQC, HMBC, H-1-H-1 COSY, and ROESY), HRMS, IR and CD spectra and by GC-FID analysis. Interestingly, the diterpene moiety of these new compounds first occurred in genus Coffea. All the isolates were evaluated for platelet aggregation activity in vitro. As the results, caffarolides C, D and F (3, 4 and 6) showed induction effect for platelet aggregation and the possible structure-activity relationships have been discussed briefly.
关键词Coffea Arabica Coffee Lipids Diterpene Esters Structure Elucidation Platelet Aggregation
DOI10.1016/j.foodchem.2018.04.081
语种英语
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文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/61334
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
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Wang, Xia,Meng, QianQian,Peng, XingRong,et al. Identification of new diterpene esters from green Arabica coffee beans, and their platelet aggregation accelerating activities[J]. FOOD CHEMISTRY,2018,263:251-257.
APA Wang, Xia,Meng, QianQian,Peng, XingRong,Hu, GuiLin,&Qiu, MingHua.(2018).Identification of new diterpene esters from green Arabica coffee beans, and their platelet aggregation accelerating activities.FOOD CHEMISTRY,263,251-257.
MLA Wang, Xia,et al."Identification of new diterpene esters from green Arabica coffee beans, and their platelet aggregation accelerating activities".FOOD CHEMISTRY 263(2018):251-257.
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