Cochlearoids L and M: Two New Meroterpenoids from the Fungus Ganoderma cochlear

	Cochlearoids L and M: Two New Meroterpenoids from the Fungus Ganoderma cochlear
	Qin, Fu-Ying 1,2; Yan, Yong-Ming 3; Tu, Zheng-Chao 4; Cheng, Yong-Xian 1,2,3
	2018-03-01
发表期刊	NATURAL PRODUCT COMMUNICATIONS
ISSN	1934-578X
卷号	13 期号:3 页码:303-305
摘要	Cochlearoids L (1) and M (2), two new meroterpenoids and three known ones, were isolated from the fruiting bodies of Ganoderma cochlear. The new structures were elucidated by spectroscopic and chemical methods. Biological evaluation showed that 1 could inhibit bromodomain-containing protein 4 (BRD4) with IC50 value of 68.7 mu M. Besides, 1 was found to have weak cytotoxic activities against three human cell lines (A549, K562, Huh-7) with IC50 values in the range of 39.6-190.0 mu M.
关键词	Ganoderma Cochlear Brd4 Cytotoxic Meroterpenoids
语种	英语
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/61331
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Henan Univ Chinese Med, Zhengzhou 450008, Henan, Peoples R China 2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 3.Shenzhen Univ, Hlth Sci Ctr, Sch Pharmaceut Sci, Shenzhen 518060, Peoples R China 4.Chinese Acad Sci, Guangzhou Inst Biomed & Hlth, Guangzhou 510530, Guangdong, Peoples R China
推荐引用方式 GB/T 7714	Qin, Fu-Ying,Yan, Yong-Ming,Tu, Zheng-Chao,et al. Cochlearoids L and M: Two New Meroterpenoids from the Fungus Ganoderma cochlear[J]. NATURAL PRODUCT COMMUNICATIONS,2018,13(3):303-305.
APA	Qin, Fu-Ying,Yan, Yong-Ming,Tu, Zheng-Chao,&Cheng, Yong-Xian.(2018).Cochlearoids L and M: Two New Meroterpenoids from the Fungus Ganoderma cochlear.NATURAL PRODUCT COMMUNICATIONS,13(3),303-305.
MLA	Qin, Fu-Ying,et al."Cochlearoids L and M: Two New Meroterpenoids from the Fungus Ganoderma cochlear".NATURAL PRODUCT COMMUNICATIONS 13.3(2018):303-305.