Nematicidal quinone derivatives from three & IT;Rubia & IT; plants
Zhao, Si-Meng3; Kuang, Bin3; Zeng, Guang-Zhi3; Wang, Zhe1,2,3; Wang, Jia1,2,3; Chen, Xiao-Qiang3; Tan, Ning-Hua1,2,3
2018-04-26
Source PublicationTETRAHEDRON
ISSN0040-4020
Volume74Issue:17Pages:2115-2120
AbstractFive new quinone derivatives, rubiasins D-F (1-3), rubialatones A and B (4 and 5), have been isolated from the roots and rhizomes of three Rubia species, Rubia alata, R. wallichiana and R. schumanniana, together with 26 known quinones (6-31). Their structures have been elucidated on the basis of NMR, MS spectra and computational methods. The compounds have been evaluated for their toxicity to the saprophytic nematode Caenorhabditis elegans and the root-knot nematode Meloidogyne incognita. Compounds 1, 6 and 7 showed toxicity to C. elegans with the LC50 values at 8.50, 9.44 and 44.82 mu g/mL, respectively; and 6 showed toxicity to M. incognita with the LC50 value at 35.22 mu g/mL. Meanwhile, compounds 1 and 6 showed inhibitory effect on egg hatch of C. elegans with the LC50 values at 5.60 and 48.95 mu g/ml. (C) 2018 Elsevier Ltd. All rights reserved.
KeywordRubia Rubia Alata Rubia Wallichiana Rubia Schumanniana Quinones Nematicidal Activity
DOI10.1016/j.tet.2018.02.065
Language英语
Citation statistics
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/60881
Collection植物化学与西部植物资源持续利用国家重点实验室
Affiliation1.China Pharmaceut Univ, Sch Tradit Chinese Pharm, Nanjing 211198, Jiangsu, Peoples R China
2.China Pharmaceut Univ, State Key Lab Nat Med, Nanjing 211198, Jiangsu, Peoples R China
3.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
Recommended Citation
GB/T 7714
Zhao, Si-Meng,Kuang, Bin,Zeng, Guang-Zhi,et al. Nematicidal quinone derivatives from three & IT;Rubia & IT; plants[J]. TETRAHEDRON,2018,74(17):2115-2120.
APA Zhao, Si-Meng.,Kuang, Bin.,Zeng, Guang-Zhi.,Wang, Zhe.,Wang, Jia.,...&Tan, Ning-Hua.(2018).Nematicidal quinone derivatives from three & IT;Rubia & IT; plants.TETRAHEDRON,74(17),2115-2120.
MLA Zhao, Si-Meng,et al."Nematicidal quinone derivatives from three & IT;Rubia & IT; plants".TETRAHEDRON 74.17(2018):2115-2120.
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