Nematicidal quinone derivatives from three & IT;Rubia & IT; plants
Zhao, Si-Meng3; Kuang, Bin3; Zeng, Guang-Zhi3; Wang, Zhe1,2,3; Wang, Jia1,2,3; Chen, Xiao-Qiang3; Tan, Ning-Hua1,2,3
2018-04-26
发表期刊TETRAHEDRON
ISSN0040-4020
卷号74期号:17页码:2115-2120
摘要Five new quinone derivatives, rubiasins D-F (1-3), rubialatones A and B (4 and 5), have been isolated from the roots and rhizomes of three Rubia species, Rubia alata, R. wallichiana and R. schumanniana, together with 26 known quinones (6-31). Their structures have been elucidated on the basis of NMR, MS spectra and computational methods. The compounds have been evaluated for their toxicity to the saprophytic nematode Caenorhabditis elegans and the root-knot nematode Meloidogyne incognita. Compounds 1, 6 and 7 showed toxicity to C. elegans with the LC50 values at 8.50, 9.44 and 44.82 mu g/mL, respectively; and 6 showed toxicity to M. incognita with the LC50 value at 35.22 mu g/mL. Meanwhile, compounds 1 and 6 showed inhibitory effect on egg hatch of C. elegans with the LC50 values at 5.60 and 48.95 mu g/ml. (C) 2018 Elsevier Ltd. All rights reserved.
关键词Rubia Rubia Alata Rubia Wallichiana Rubia Schumanniana Quinones Nematicidal Activity
DOI10.1016/j.tet.2018.02.065
语种英语
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文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/60881
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.China Pharmaceut Univ, Sch Tradit Chinese Pharm, Nanjing 211198, Jiangsu, Peoples R China
2.China Pharmaceut Univ, State Key Lab Nat Med, Nanjing 211198, Jiangsu, Peoples R China
3.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
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Zhao, Si-Meng,Kuang, Bin,Zeng, Guang-Zhi,et al. Nematicidal quinone derivatives from three & IT;Rubia & IT; plants[J]. TETRAHEDRON,2018,74(17):2115-2120.
APA Zhao, Si-Meng.,Kuang, Bin.,Zeng, Guang-Zhi.,Wang, Zhe.,Wang, Jia.,...&Tan, Ning-Hua.(2018).Nematicidal quinone derivatives from three & IT;Rubia & IT; plants.TETRAHEDRON,74(17),2115-2120.
MLA Zhao, Si-Meng,et al."Nematicidal quinone derivatives from three & IT;Rubia & IT; plants".TETRAHEDRON 74.17(2018):2115-2120.
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