Nematicidal quinone derivatives from three & IT;Rubia & IT; plants

doi:10.1016/j.tet.2018.02.065

	Nematicidal quinone derivatives from three & IT;Rubia & IT; plants
	Zhao, Si-Meng 3; Kuang, Bin 3; Zeng, Guang-Zhi 3; Wang, Zhe1,2,3 ; Wang, Jia 1,2,3; Chen, Xiao-Qiang 3; Tan, Ning-Hua 1,2,3
	2018-04-26
发表期刊	TETRAHEDRON
ISSN	0040-4020
卷号	74 期号:17 页码:2115-2120
摘要	Five new quinone derivatives, rubiasins D-F (1-3), rubialatones A and B (4 and 5), have been isolated from the roots and rhizomes of three Rubia species, Rubia alata, R. wallichiana and R. schumanniana, together with 26 known quinones (6-31). Their structures have been elucidated on the basis of NMR, MS spectra and computational methods. The compounds have been evaluated for their toxicity to the saprophytic nematode Caenorhabditis elegans and the root-knot nematode Meloidogyne incognita. Compounds 1, 6 and 7 showed toxicity to C. elegans with the LC50 values at 8.50, 9.44 and 44.82 mu g/mL, respectively; and 6 showed toxicity to M. incognita with the LC50 value at 35.22 mu g/mL. Meanwhile, compounds 1 and 6 showed inhibitory effect on egg hatch of C. elegans with the LC50 values at 5.60 and 48.95 mu g/ml. (C) 2018 Elsevier Ltd. All rights reserved.
关键词	Rubia Rubia Alata Rubia Wallichiana Rubia Schumanniana Quinones Nematicidal Activity
DOI	10.1016/j.tet.2018.02.065
语种	英语
引用统计	被引频次：11[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/60881
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.China Pharmaceut Univ, Sch Tradit Chinese Pharm, Nanjing 211198, Jiangsu, Peoples R China 2.China Pharmaceut Univ, State Key Lab Nat Med, Nanjing 211198, Jiangsu, Peoples R China 3.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
推荐引用方式 GB/T 7714	Zhao, Si-Meng,Kuang, Bin,Zeng, Guang-Zhi,et al. Nematicidal quinone derivatives from three & IT;Rubia & IT; plants[J]. TETRAHEDRON,2018,74(17):2115-2120.
APA	Zhao, Si-Meng.,Kuang, Bin.,Zeng, Guang-Zhi.,Wang, Zhe.,Wang, Jia.,...&Tan, Ning-Hua.(2018).Nematicidal quinone derivatives from three & IT;Rubia & IT; plants.TETRAHEDRON,74(17),2115-2120.
MLA	Zhao, Si-Meng,et al."Nematicidal quinone derivatives from three & IT;Rubia & IT; plants".TETRAHEDRON 74.17(2018):2115-2120.

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