New C-16-noriridals and formyl-monocycloiridals from the rhizomes of Iris pseudoacorus
Chen, Xinglong1,3; Zhang, Xiugiong1,3; Geng, Changan1,2; Li, Tianze1,2; Chen, Jijun1,2
2018
发表期刊FITOTERAPIA
ISSN0367-326X
卷号124页码:160-166
摘要Four new C-16-noriridals (1-4) and two reported C-16-noriridals (5-6), together with two new formyl-monocycloiridals (7-8) and three known monocycloiridals (9-11) were isolated from the rhizomes of Iris pseudoacorus. Irispseudoacorins A-D (1-4) and iridojaponals A-B (5-6) were C-16-noriridals which shared a 6/5/7 tricyclic ring system (1-2, 5-6) or 6/5 tricyclic ring system (3-4). The formyl-monocycloiridals (7-8) were detected in the crude extracts of I. pseudoacorus by LC-MS analysis which suggested they were originated from natural sources rather than artificial products during the isolation. Their structures were determined by UV, IR, extensive NMR spectra and X-ray diffraction analyses. The known monocycloiridals 9-10 displayed pronounced cytotoxic effects against five human tumor cell lines. The IC50 values of 9 were ranging from 12.63 to 24.69 mu M.
关键词Iris Pseudoacorus C-16-noriridal Lc-ms Cytotoxic Activity
语种英语
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文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/60576
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, 132 Lanhei Rd, Kunming 650201, Yunnan, Peoples R China
2.Yunnan Key Lab Nat Med Chem, Kunming 650201, Yunnan, Peoples R China
3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
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Chen, Xinglong,Zhang, Xiugiong,Geng, Changan,et al. New C-16-noriridals and formyl-monocycloiridals from the rhizomes of Iris pseudoacorus[J]. FITOTERAPIA,2018,124:160-166.
APA Chen, Xinglong,Zhang, Xiugiong,Geng, Changan,Li, Tianze,&Chen, Jijun.(2018).New C-16-noriridals and formyl-monocycloiridals from the rhizomes of Iris pseudoacorus.FITOTERAPIA,124,160-166.
MLA Chen, Xinglong,et al."New C-16-noriridals and formyl-monocycloiridals from the rhizomes of Iris pseudoacorus".FITOTERAPIA 124(2018):160-166.
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