Meroterpenoids from the fruiting bodies of Ganoderma theaecolum
Luo, Qi1,5; Tu, Zheng-Chao4; Yang, Zhu-Liang1; Cheng, Yong-Xian1,2,3
2018-03-01
发表期刊FITOTERAPIA
ISSN0367-326X
卷号125页码:273-280
摘要A series of new terminal cyclohexane-type meroterpenoids, ganotheaecoloids A - N (1 - 6, 8 - 13, 15, and 16), along with three known ones (7, 14, and 17), were isolated from the dried fruiting bodies of Ganoderma theaecolum. Their chemical structures were identified by using spectroscopic data and computational methods. Biological activity of all the new meroterpenoids against COX-2 was evaluated in vitro, only ganotheaecoloid J (11) was found to have COX-2 inhibitory activity with IC50 value of 9.96 mu M.
关键词Ganoderma Theaecolum Meroterpenoids Ganotheaecoloids a - n Ecd Calculations Cox-2
语种英语
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文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/60553
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, Key Lab Plant Divers & Biogeog East Asia, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
2.Shenzhen Univ, Hlth Sci Ctr, Sch Pharmaceut Sci, Sch Med,Guangdong Key Lab Genome Stabil & Dis Pre, Shenzhen 518060, Peoples R China
3.Henan Univ Chinese Med, Zhengzhou 450008, Henan, Peoples R China
4.Guangzhou Inst Biomed & Hlth, Drug Discovery Pipeline & Guangdong Prov Key Lab, Guangzhou 510530, Guangdong, Peoples R China
5.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
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Luo, Qi,Tu, Zheng-Chao,Yang, Zhu-Liang,et al. Meroterpenoids from the fruiting bodies of Ganoderma theaecolum[J]. FITOTERAPIA,2018,125:273-280.
APA Luo, Qi,Tu, Zheng-Chao,Yang, Zhu-Liang,&Cheng, Yong-Xian.(2018).Meroterpenoids from the fruiting bodies of Ganoderma theaecolum.FITOTERAPIA,125,273-280.
MLA Luo, Qi,et al."Meroterpenoids from the fruiting bodies of Ganoderma theaecolum".FITOTERAPIA 125(2018):273-280.
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