Chromanopyrones and a flavone from Hypericum monogynum

doi:10.1016/j.fitote.2017.12.013

	Chromanopyrones and a flavone from Hypericum monogynum
	Zeng, Yan-Rong 1,2,3; Wang, Li-Ping 1,2,3; Hu, Zhan-Xing1,3 ; Yi, Ping 1,2,3; Yang, Wan-Xia 1,2,3; Gu, Wei1,2,3 ; Huang, Lie-Jun 1,2,3; Yuan, Chun-Mao 1,2,3; Hao, Xiao-Jiang1,2,3,4
	2018-03-01
发表期刊	FITOTERAPIA
ISSN	0367-326X
卷号	125 页码:59-64
摘要	Six new compounds, including three pyrone derivatives (2-4), one new flavone (5), and two new naturally-occurring compounds (1 and 6), together with 16 known compounds were isolated from the leaves and twigs of Hypericum monogynum. In addition, compounds 2-4 are racemates. Their structures and absolute configurations were determined on the basis of extensive analysis of spectroscopic data and ECD calculation. All compounds were evaluated for the inhibitory effects on alpha-glucosidase, compounds 1, 5, and 7 showed moderate inhibitory activities with IC50 values of 161.46, 257.78, and 11.54 mu g/ml, respectively. Compound 8 exhibited weak antioxidant activity with IC50 value of 12.55 mu g/ml.
关键词	Hypericum Monogynum Pyrone Derivatives Inhibitory Effects On Alpha-glucosidase Anti-oxidant Activity
DOI	10.1016/j.fitote.2017.12.013
语种	英语
WOS记录号	WOS:000425560500010
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/60549
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Guizhou Med Univ, State Key Lab Funct & Applicat Med Plants, Guiyang 550014, Guizhou, Peoples R China 2.Guizhou Med Univ, Sch Pharmacuet Sci, Guiyang 550025, Guizhou, Peoples R China 3.Chinese Acad Sci, Key Lab Chem Nat Prod Guizhou Prov, Guiyang 550014, Guizhou, Peoples R China 4.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
推荐引用方式 GB/T 7714	Zeng, Yan-Rong,Wang, Li-Ping,Hu, Zhan-Xing,et al. Chromanopyrones and a flavone from Hypericum monogynum[J]. FITOTERAPIA,2018,125:59-64.
APA	Zeng, Yan-Rong.,Wang, Li-Ping.,Hu, Zhan-Xing.,Yi, Ping.,Yang, Wan-Xia.,...&Hao, Xiao-Jiang.(2018).Chromanopyrones and a flavone from Hypericum monogynum.FITOTERAPIA,125,59-64.
MLA	Zeng, Yan-Rong,et al."Chromanopyrones and a flavone from Hypericum monogynum".FITOTERAPIA 125(2018):59-64.