Chromanopyrones and a flavone from Hypericum monogynum
Zeng, Yan-Rong1,2,3; Wang, Li-Ping1,2,3; Hu, Zhan-Xing1,3; Yi, Ping1,2,3; Yang, Wan-Xia1,2,3; Gu, Wei1,2,3; Huang, Lie-Jun1,2,3; Yuan, Chun-Mao1,2,3; Hao, Xiao-Jiang1,2,3,4
2018-03-01
发表期刊FITOTERAPIA
ISSN0367-326X
卷号125页码:59-64
摘要Six new compounds, including three pyrone derivatives (2-4), one new flavone (5), and two new naturally-occurring compounds (1 and 6), together with 16 known compounds were isolated from the leaves and twigs of Hypericum monogynum. In addition, compounds 2-4 are racemates. Their structures and absolute configurations were determined on the basis of extensive analysis of spectroscopic data and ECD calculation. All compounds were evaluated for the inhibitory effects on alpha-glucosidase, compounds 1, 5, and 7 showed moderate inhibitory activities with IC50 values of 161.46, 257.78, and 11.54 mu g/ml, respectively. Compound 8 exhibited weak antioxidant activity with IC50 value of 12.55 mu g/ml.
关键词Hypericum Monogynum Pyrone Derivatives Inhibitory Effects On Alpha-glucosidase Anti-oxidant Activity
语种英语
引用统计
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/60549
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Guizhou Med Univ, State Key Lab Funct & Applicat Med Plants, Guiyang 550014, Guizhou, Peoples R China
2.Guizhou Med Univ, Sch Pharmacuet Sci, Guiyang 550025, Guizhou, Peoples R China
3.Chinese Acad Sci, Key Lab Chem Nat Prod Guizhou Prov, Guiyang 550014, Guizhou, Peoples R China
4.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
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Zeng, Yan-Rong,Wang, Li-Ping,Hu, Zhan-Xing,et al. Chromanopyrones and a flavone from Hypericum monogynum[J]. FITOTERAPIA,2018,125:59-64.
APA Zeng, Yan-Rong.,Wang, Li-Ping.,Hu, Zhan-Xing.,Yi, Ping.,Yang, Wan-Xia.,...&Hao, Xiao-Jiang.(2018).Chromanopyrones and a flavone from Hypericum monogynum.FITOTERAPIA,125,59-64.
MLA Zeng, Yan-Rong,et al."Chromanopyrones and a flavone from Hypericum monogynum".FITOTERAPIA 125(2018):59-64.
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