Backbone and side-chain chemical shift assignments of the kringle domain of human receptor tyrosine kinase-like orphan receptor 1 (ROR1) | |
Ma, Xiaofang1; Zhang, Yingying1; Liu, Bin1; Yang, Jiahui1,2; Hu, Kaifeng1 | |
2018-04-01 | |
发表期刊 | BIOMOLECULAR NMR ASSIGNMENTS |
ISSN | 1874-2718 |
卷号 | 12期号:1页码:145-148 |
摘要 | Receptor tyrosine kinase-like orphan receptor 1 (ROR1) expresses at high level in many cancers and has been suggested as a potential therapeutic target. It was reported that the Kringle (KNG) domain of ROR1 extracellular region is involved in ROR1/ROR2 heterooligomerization. Monoantibodies that target KNG domain of ROR1 could induce apoptosis of chronic lymphocytic leukemia cells. Here we present the backbone and side chain assignments of KNG domain of ROR1, which lays a foundation for its further structural and function research. |
关键词 | Ror1 Kringle Nmr |
DOI | 10.1007/s12104-017-9797-9 |
语种 | 英语 |
WOS记录号 | WOS:000428448100028 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.kib.ac.cn/handle/151853/60514 |
专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, 132 Lanhei Rd, Kunming 650201, Yunnan, Peoples R China 2.Chengdu Univ TCM, Sch Basic Med, 1166 Liutai Ave, Chengdu 611137, Sichuan, Peoples R China |
推荐引用方式 GB/T 7714 | Ma, Xiaofang,Zhang, Yingying,Liu, Bin,et al. Backbone and side-chain chemical shift assignments of the kringle domain of human receptor tyrosine kinase-like orphan receptor 1 (ROR1)[J]. BIOMOLECULAR NMR ASSIGNMENTS,2018,12(1):145-148. |
APA | Ma, Xiaofang,Zhang, Yingying,Liu, Bin,Yang, Jiahui,&Hu, Kaifeng.(2018).Backbone and side-chain chemical shift assignments of the kringle domain of human receptor tyrosine kinase-like orphan receptor 1 (ROR1).BIOMOLECULAR NMR ASSIGNMENTS,12(1),145-148. |
MLA | Ma, Xiaofang,et al."Backbone and side-chain chemical shift assignments of the kringle domain of human receptor tyrosine kinase-like orphan receptor 1 (ROR1)".BIOMOLECULAR NMR ASSIGNMENTS 12.1(2018):145-148. |
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