角蒿中的环己乙醇类化学成分研究
李钦 ; 沈月毛 ; 张评浒 ; 张陆勇 ; 李萍
2008
Source Publication中山大学学报:自然科学版
ISSN0529-6579
Volume47Issue:5Pages:58-62
Abstract利用Sephadex LH-20及硅胶等柱色谱技术从药用民族植物角蒿(Incarvillea dissectifoliola Q.S.Zhao)的根茎中分离得到了11个环己乙醇类化合物。经理化数据对照和波谱分析,确定它们的结构分别为rengyolone(1),(3aS,6R)-2,3,3a,6,7,7a-hexahydrobenzofuran-3a,6-diol(2),(3aR)-hexahydro-3a—hydroxybenzofuran-6(2H)-one(3),(3aR,6R)-octahydrobenzofuran-3a,6-diol(4),(3aR,6S)-octahydrobenzofuran-3a,6-diol(5),4-hydroxy-4-(2-hydroxyethyl)cyclohexanone(6),(3aS,4S)-hexahydro-3a,4-dihydroxybenzofuran-6(2H)-one(7),(3aR,4S)-hexa—hydro-3a,4-dihydroxy benzofuran-6(2H)-one(8),rengyol(9),isorengyol(10)和rengyosideB(11)。这11个化合物均为首次从角蒿中分离得到。化合物4,5,6,7,8,9,10的细胞毒活性未见报道,对它们的细胞毒活性进行了测定,结果表明它们对HL-60细胞株的IC50分别为102,44.7,24.6,98.0,47.8,25.3,92.3和47.2μmoL/L。
Keyword角蒿 环己乙醇 化学成分 细胞毒实验
Indexed Bycscd
Language中文
CSCD IDCSCD:3425032
Citation statistics
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/5785
Collection植物化学与西部植物资源持续利用国家重点实验室
Recommended Citation
GB/T 7714
李钦,沈月毛,张评浒,等. 角蒿中的环己乙醇类化学成分研究[J]. 中山大学学报:自然科学版,2008,47(5):58-62.
APA 李钦,沈月毛,张评浒,张陆勇,&李萍.(2008).角蒿中的环己乙醇类化学成分研究.中山大学学报:自然科学版,47(5),58-62.
MLA 李钦,et al."角蒿中的环己乙醇类化学成分研究".中山大学学报:自然科学版 47.5(2008):58-62.
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