| Dibenzocyclooctadiene lignans from the fruits of Schisandra rubriflora and their anti-HIV-1 activities | |
Mu, Huai-Xue1,2,3,4; Li, Xue-Sen1,2,4; Fan, Peng1,2,4; Yang, Guang-Yu1,2,3,4; Pu, Jian-Xin3 ; Sun, Han-Dong3; Hu, Qiu-Fen1,2; Xiao, Wei-Lie3
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| 通讯作者 | Hu, QF (reprint author), Yunnan Univ Nationalities, Key Lab Ethn Med Resource Chem, State Ethn Affairs Commiss, Kunming 650031, Peoples R China |
| 2011 | |
| 发表期刊 | JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
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| ISSN | 1028-6020 |
| 卷号 | 13期号:5页码:393-399 |
| 摘要 | Two new dibenzocyclooctadiene lignans, rubrilignans A and B (1, 2), together with 17 known ones, were isolated from the fruits of Schisandra rubriflora. The structures of 1 and 2 were elucidated by spectroscopic methods including extensive 1D and 2D NMR techniques. Compounds 1 and 2 were also evaluated for their anti-HIV-1 activities and showed weak anti-HIV-1 activity with EC50 values of 2.26 and 1.82g/ml, and therapeutic index values of 35.5 and 18.6, respectively. |
| 关键词 | Schisandreae Schisandra Rubriflora Fruits Dibenzocyclooctadiene Lignans Anti-hiv-1 Activity |
| 学科领域 | Plant Sciences ; Chemistry ; Pharmacology & Pharmacy |
| DOI | 10.1080/10286020.2011.565748 |
| 收录类别 | SCI ; IC |
| 语种 | 英语 |
| WOS记录号 | WOS:000290046300002 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kib.ac.cn/handle/151853/5503 |
| 专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Yunnan Univ Nationalities, Key Lab Ethn Med Resource Chem, State Ethn Affairs Commiss, Kunming 650031, Peoples R China 2.Minist Educ, Kunming 650031, Peoples R China 3.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China 4.Yunnan Acad Tobacco Sci, Key Lab Tobacco Chem Yunnan Prov, Kunming 650106, Peoples R China |
| 推荐引用方式 GB/T 7714 | Mu, Huai-Xue,Li, Xue-Sen,Fan, Peng,et al. Dibenzocyclooctadiene lignans from the fruits of Schisandra rubriflora and their anti-HIV-1 activities[J]. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,2011,13(5):393-399. |
| APA | Mu, Huai-Xue.,Li, Xue-Sen.,Fan, Peng.,Yang, Guang-Yu.,Pu, Jian-Xin.,...&Xiao, Wei-Lie.(2011).Dibenzocyclooctadiene lignans from the fruits of Schisandra rubriflora and their anti-HIV-1 activities.JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,13(5),393-399. |
| MLA | Mu, Huai-Xue,et al."Dibenzocyclooctadiene lignans from the fruits of Schisandra rubriflora and their anti-HIV-1 activities".JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH 13.5(2011):393-399. |
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