Dibenzocyclooctadiene lignans from Schisandra neglecta and their anti-HIV-1 activities
Duan, Yuan-Xing1,2,3,4; Cao, Jing-Li2,3,4; Wen, Rong-Rong2,3,4; Yang, Guang-Yu1,2,3,4; Pu, Jian-Xin1; Sun, Han-Dong1; Xiao, Wei-Lie1; Li, Gan-Peng1,2,3
2011
发表期刊JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
ISSN1028-6020
卷号13期号:7页码:592-598
摘要Two new dibenzocyclooctadiene lignans, schinegllignans A and B (1 and 2), together with 11 known (3 13) were isolated from the fruit of Schisandra neglecta. Their structures and stereochemistries were elucidated by spectroscopic methods, including 1D, 2D NMR, and HR-ESI-MS techniques. Compounds 1 and 2 were evaluated for their anti-HIV activities, and they showed moderate anti-HIV-1 activities with therapeutic index values of 18.5 and 24.6.
关键词Schisandra Neglecta Dibenzocyclooctadiene Lignans Schinegllignans a And b Anti-hiv-1 Activities
资助信息Natural Science Foundation of China[30830115, 20802082]; Chinese Academy of Sciences[KSCX1-YW-R-24]; 973 Program[2009CB522303, 2009CB522306, 2009CB940900]; Scientific and Technological projects of China[2009ZX09501-029]; Young Academic and Technical Leader Rising Foundation of Yunnan Province[2006PY01-47]; Natural Science Foundation of Yunnan Province[2005XY04, 2006B0042Q]
学科领域Plant Sciences ; Chemistry ; Pharmacology & Pharmacy
DOI10.1080/10286020.2011.576843
收录类别SCI ; IC
语种英语
WOS研究方向Plant Sciences ; Chemistry ; Pharmacology & Pharmacy
WOS类目Plant Sciences ; Chemistry, Applied ; Chemistry, Medicinal ; Pharmacology & Pharmacy
WOS记录号WOS:000294801900003
引用统计
被引频次:5[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/5501
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Peoples R China
2.Yunnan Univ Nationalities, Key Lab Ethn Med Resource Chem, State Ethn Affairs Commiss, Kunming 650031, Peoples R China
3.Minist Educ, Kunming 650031, Peoples R China
4.Yunnan Acad Tobacco Sci, Key Lab Tobacco Chem Yunnan Prov, Kunming 650106, Peoples R China
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Duan, Yuan-Xing,Cao, Jing-Li,Wen, Rong-Rong,et al. Dibenzocyclooctadiene lignans from Schisandra neglecta and their anti-HIV-1 activities[J]. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,2011,13(7):592-598.
APA Duan, Yuan-Xing.,Cao, Jing-Li.,Wen, Rong-Rong.,Yang, Guang-Yu.,Pu, Jian-Xin.,...&Li, Gan-Peng.(2011).Dibenzocyclooctadiene lignans from Schisandra neglecta and their anti-HIV-1 activities.JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,13(7),592-598.
MLA Duan, Yuan-Xing,et al."Dibenzocyclooctadiene lignans from Schisandra neglecta and their anti-HIV-1 activities".JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH 13.7(2011):592-598.
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