Four Hybrid Flavan-Chalcones, Caesalpinnone A Possessing a 10,11-Dioxatricyclic [5.3.3.0(1,6)]Tridecane-Bridged System and Caesalpinflavans A-C from Caesalpinia enneaphylla

doi:10.1021/acs.orglett.7b01955

	Four Hybrid Flavan-Chalcones, Caesalpinnone A Possessing a 10,11-Dioxatricyclic [5.3.3.0(1,6)]Tridecane-Bridged System and Caesalpinflavans A-C from Caesalpinia enneaphylla
	Zhang, Lan-Jun 1; Bi, De-Wen 1; Hu, Jiangmiao2 ; Mu, Wei-Hua 1; Li, Yuan-Ping 1; Xia, Guang-Hui 1; Yang, Liu 2; Li, Xiao-Nian 2; Liang, Xue-Song 1; Wang, Li-Qin 1
	2017-08-18
发表期刊	ORGANIC LETTERS
ISSN	1523-7060
卷号	19 期号:16 页码:4315-4318
摘要	Caesalpinnone A (1), an unprecedented hybrid of flavan and chalcone, possessing a 10,11-dioxatricyclic [5.3.3.0(1,6)]tridecane-bridged system, and caesalpinflavans A-C (2-4), three new hybrid flavan-chalcones, were isolated from the twigs and leaves of Caesalpinia enneaphylla. Their structures were elucidated by a combination of spectroscopic analyses and single-crystal X-ray diffraction. Caesalpinnone A showed the highest cytotoxicity against the HL-60, SMMC-7721, A-549, MCF-7, and SW-480 human tumor cell lines with an IC50 in the range of 0.54-0.87 mu M.
关键词	Cassane Diterpenes Sappan
学科领域	Chemistry, Organic
DOI	10.1021/acs.orglett.7b01955
收录类别	SCI
语种	英语
WOS记录号	WOS:000408285600041
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/54916
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Yunnan Normal Univ, Fac Chem & Chem Engn, Kunming 650050, Yunnan, Peoples R China 2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
推荐引用方式 GB/T 7714	Zhang, Lan-Jun,Bi, De-Wen,Hu, Jiangmiao,et al. Four Hybrid Flavan-Chalcones, Caesalpinnone A Possessing a 10,11-Dioxatricyclic [5.3.3.0(1,6)]Tridecane-Bridged System and Caesalpinflavans A-C from Caesalpinia enneaphylla[J]. ORGANIC LETTERS,2017,19(16):4315-4318.
APA	Zhang, Lan-Jun.,Bi, De-Wen.,Hu, Jiangmiao.,Mu, Wei-Hua.,Li, Yuan-Ping.,...&Wang, Li-Qin.(2017).Four Hybrid Flavan-Chalcones, Caesalpinnone A Possessing a 10,11-Dioxatricyclic [5.3.3.0(1,6)]Tridecane-Bridged System and Caesalpinflavans A-C from Caesalpinia enneaphylla.ORGANIC LETTERS,19(16),4315-4318.
MLA	Zhang, Lan-Jun,et al."Four Hybrid Flavan-Chalcones, Caesalpinnone A Possessing a 10,11-Dioxatricyclic [5.3.3.0(1,6)]Tridecane-Bridged System and Caesalpinflavans A-C from Caesalpinia enneaphylla".ORGANIC LETTERS 19.16(2017):4315-4318.

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