Swerilactones L-O, Secoiridoids with C(12) and C(13) Skeletons from Swertia mileensis
Geng, CA ; Zhang, XM ; Ma, YB ; Luo, J ; Chen, JJ
2011
发表期刊JOURNAL OF NATURAL PRODUCTS
ISSN0163-3864
卷号74期号:8页码:1822-1825
摘要Swerilactones L-O (1-4), four unusual secoiridoids with unprecedented C(12) and C(13) skeletons, were isolated from the traditional Chinese herb Swertia mileensis. Compounds 1 and 2 had moderate inhibitory activities against the secretion of hepatitis B virus surface antigen (IC(50) = 1.47 and 1.20 mM, with SI < 1 and 1.53, respectively) and hepatitis B virus e antigen (IC(50) = 0.88 and > 2.69 mM, with SI 1.62 and < 1, respectively) in an antihepatitis B virus assay on the Hep G 2.2.15 cell line in vitro.
关键词Iridoids Alkaloids Constituents
资助信息National Natural Science Foundation of China and Yunnan Province[U0832603]; National Natural Science Foundation of China for Distinguished Young Scholars[81025023]; Major Project of Innovative Engineering[KSCX2-YW-R-181]; Chinese Academy of Sciences; State Key Laboratory of Phytochemistry and Plant Resources in West China[P2010-ZZ08]
学科领域Plant Sciences ; Pharmacology & Pharmacy
收录类别sci
语种英语
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/5483
专题植物化学与西部植物资源持续利用国家重点实验室
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GB/T 7714
Geng, CA,Zhang, XM,Ma, YB,et al. Swerilactones L-O, Secoiridoids with C(12) and C(13) Skeletons from Swertia mileensis[J]. JOURNAL OF NATURAL PRODUCTS,2011,74(8):1822-1825.
APA Geng, CA,Zhang, XM,Ma, YB,Luo, J,&Chen, JJ.(2011).Swerilactones L-O, Secoiridoids with C(12) and C(13) Skeletons from Swertia mileensis.JOURNAL OF NATURAL PRODUCTS,74(8),1822-1825.
MLA Geng, CA,et al."Swerilactones L-O, Secoiridoids with C(12) and C(13) Skeletons from Swertia mileensis".JOURNAL OF NATURAL PRODUCTS 74.8(2011):1822-1825.
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