Three new acorane sesquiterpenes from Trichoderma sp YMF1.02647
Li, Guo-Hong1; Yang, Zhong-Shan1; Zhao, Pei-Ji2; Zheng, Xi1; Luo, Shao-Liu1; Sun, Rong1; Niu, Xue-Mei1; Zhang, Ke-Qin1
2011-06-15
发表期刊PHYTOCHEMISTRY LETTERS
ISSN1874-3900
卷号4期号:2页码:86-88
摘要Three new acorane sesquiterpenes 1 alpha-isopropyl-4 alpha, 8-dimethylspiro[4.5]dec-8-ene-2 beta, 7 alpha-diol (1), 1 alpha-isopropyl- 4 alpha, 8-dimethylspiro[4.5] dec-8-ene-3 beta, 7 alpha-diol (2) and 2 beta-hydroxy-1 alpha-isopropyl-4 alpha, 8dimethylspiro[4.5]dec-8-en-7-one (3) were isolated from the culture broth of Trichoderma sp. YMF1.02647. The structures were elucidated using spectroscopic data from 1D, 2D NMR and HRESIMS experiments, and the structure of 1 was further confirmed by a single-crystal X-ray diffraction analysis. Antitumor activity experiment showed that compound 2 had inhibitive activity against HL-60, A-549 and MCF-7 cell lines. (C) 2010 Phytochemical Society of Europe. Published by Elsevier B. V. All rights reserved.
关键词Acorane Sesquiterpenes Trichoderma Sp. Antitumor Activity
资助信息National Basic Research Program of China (973 Program)[2007CB411600, 2009CB125905]; National Natural Science Foundation of China[30960007]; Fund of State Key Laboratory of Phytochemistry and Plant Resources in West China[P2009-KF07]; Young Academic and Technical Leader Raising Foundation of Yunnan Province; Yunnan Provincial Company of China National Tobacco Corporation
学科领域Biochemistry & Molecular Biology ; Plant Sciences
DOI10.1016/j.phytol.2010.09.005
收录类别SCI
语种英语
WOS研究方向Biochemistry & Molecular Biology ; Plant Sciences
WOS类目Biochemistry & Molecular Biology ; Plant Sciences
WOS记录号WOS:000290788100006
引用统计
被引频次:6[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/5445
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Yunnan Univ, Key Lab Conservat & Utilizat Bioresource, Kunming 650091, Yunnan, Peoples R China
2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China
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Li, Guo-Hong,Yang, Zhong-Shan,Zhao, Pei-Ji,et al. Three new acorane sesquiterpenes from Trichoderma sp YMF1.02647[J]. PHYTOCHEMISTRY LETTERS,2011,4(2):86-88.
APA Li, Guo-Hong.,Yang, Zhong-Shan.,Zhao, Pei-Ji.,Zheng, Xi.,Luo, Shao-Liu.,...&Zhang, Ke-Qin.(2011).Three new acorane sesquiterpenes from Trichoderma sp YMF1.02647.PHYTOCHEMISTRY LETTERS,4(2),86-88.
MLA Li, Guo-Hong,et al."Three new acorane sesquiterpenes from Trichoderma sp YMF1.02647".PHYTOCHEMISTRY LETTERS 4.2(2011):86-88.
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