中国科学院昆明植物研究所机构知识库
Advanced  
KIB OpenIR  > 植物化学与西部植物资源持续利用国家重点实验室  > 期刊论文
题名: Lyonin A, a New 9,10-Secograyanotoxin from Lyonia ovalifolia
作者: Wu, Zhao-Yuan1, 2; Li, Hai-Zhou2; Wang, Wei-Guang2; Li, Hong-Mei2; Chen, Rui3; Li, Rong-Tao1, 2; null(罗怀容)3
刊名: CHEMISTRY & BIODIVERSITY
关键词: ELLIPTICA HAND-MAZZ ; TRITERPENOID GLUCOSIDE ; LYOFOLIC ACID ; CONSTITUENTS
英文摘要: Phytochemical studies on the branches and leaves of Lyonia ovalifolia yielded a new grayanane diterpenoid, lyonin A (1), together with two known compounds, secorhodomollolides A and D (2 and 3, resp.). The structure of 1 was elucidated by combination of 1D- and 2D-NMR, and MS analyses. Compound 1 turned out to be a new, highly O-acylated grayanane diterpenoid, of which ring B has undergone an oxidative cleavage between C(9) and C(10), yielding a system differing from the previously reported grayanane type with a 5/7/6/5 ring system. Results of the cAMP regulation activity assay showed that compounds 2 and 3 at 50 mu m induced a significantly decreased cAMP level in N1E-115 neuroblastoma cells (p < 0.001), indicating neuropharmacological potential.
出版日期: 2011-06-01
卷号: 8, 期号:6, 页码:1182-1187
语种: 英语
收录类别: SCI
学科分类: Biochemistry & Molecular Biology; Chemistry
ISSN号: 1612-1872
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/5415
Appears in Collections:植物化学与西部植物资源持续利用国家重点实验室_期刊论文

Files in This Item: Download All
File Name/ File Size Content Type Version Access License
201203190085.pdf(178KB)----开放获取--View Download

作者单位: 1.Kunming Univ Sci & Technol, Coll Environm Sci & Engn, Kunming 650224, Peoples R China
2.Kunming Univ Sci & Technol, Coll Life Sci & Technol, Kunming 650224, Peoples R China
3.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China

Recommended Citation:
Wu, ZY; Li, HZ; Wang, WG; Li, HM; Chen, R; Li, RT; Luo, HR.Lyonin A, a New 9,10-Secograyanotoxin from Lyonia ovalifolia,CHEMISTRY & BIODIVERSITY,2011,8(6):1182-1187
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Wu, Zhao-Yuan]'s Articles
[Li, Hai-Zhou]'s Articles
[Wang, Wei-Guang]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Wu, Zhao-Yuan]‘s Articles
[Li, Hai-Zhou]‘s Articles
[Wang, Wei-Guang]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit
文件名: 201203190085.pdf
格式: Adobe PDF
此文件暂不支持浏览
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2017  中国科学院昆明植物研究所 - Feedback
Powered by CSpace