Sesquiterpenoids and Lignans from the Roots of Valeriana officinalis L.
Wang, Peng-Cheng1,3; Ran, Xin-Hui1; Chen, Rui1; Luo, Huai-Rong1; Ma, Qing-Yun2; Liu, Yu-Qing1; Hu, Jiang-Miao1; Huang, Sheng-Zhuo1; Jiang, He-Zhong1; Chen, Zhong-Quan1; Zhou, Jun1; Zhao, You-Xing1,2
Corresponding AuthorZhou, J (reprint author), Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China
2011-10-01
Source PublicationCHEMISTRY & BIODIVERSITY
ISSN1612-1872
Volume8Issue:10Pages:1908-1913
AbstractTwo new guaiane-type sesquiterpenoids, valerol A (1) and kessyl 3-acetate (2), together with nine known compounds, valeracetate (3), anismol A (4), orientalol C (5), spatulenol (6), 4 alpha, 10 alpha-epoxyaromadendrane (7), (+)-8-hydroxypinoresinol (8), pinorespiol (9), pinoresinol 4-O-beta-D-glucopyranoside (10), and 8-hydroxypinoresinol 4'-O-beta-D-glucopyranoside (11) were isolated from the roots of Valeriana officinalis. The structures and relative configurations of 1 and 2 were elucidated on the basis of spectroscopic methods (1D- and 2D-NMR, MS, UV, and IR). These compounds were evaluated for inhibitory activity on acetylcholinesterase (AChE) and enhancing activity on nerve growth factor (NGF)-mediated neurite outgrowth in PC12 cells.
KeywordNerve Growth-factor Rat Identification Constituents Receptors Jatamansi Cells
Subject AreaBiochemistry & Molecular Biology ; Chemistry
Indexed BySCI
Language英语
WOS Research AreaBiochemistry & Molecular Biology ; Chemistry
WOS SubjectBiochemistry & Molecular Biology ; Chemistry, Multidisciplinary
WOS IDWOS:000296503800010
Citation statistics
Cited Times:19[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/5413
Collection植物化学与西部植物资源持续利用国家重点实验室
Affiliation1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China
2.Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Haikou 571101, Peoples R China
3.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
Recommended Citation
GB/T 7714
Wang, Peng-Cheng,Ran, Xin-Hui,Chen, Rui,et al. Sesquiterpenoids and Lignans from the Roots of Valeriana officinalis L.[J]. CHEMISTRY & BIODIVERSITY,2011,8(10):1908-1913.
APA Wang, Peng-Cheng.,Ran, Xin-Hui.,Chen, Rui.,Luo, Huai-Rong.,Ma, Qing-Yun.,...&Zhao, You-Xing.(2011).Sesquiterpenoids and Lignans from the Roots of Valeriana officinalis L..CHEMISTRY & BIODIVERSITY,8(10),1908-1913.
MLA Wang, Peng-Cheng,et al."Sesquiterpenoids and Lignans from the Roots of Valeriana officinalis L.".CHEMISTRY & BIODIVERSITY 8.10(2011):1908-1913.
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