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题名: Sesquiterpenoids and Lignans from the Roots of Valeriana officinalis L.
作者: Wang, Peng-Cheng1, 3; Ran, Xin-Hui1; Chen, Rui1; null(罗怀容)1; Ma, Qing-Yun2; Liu, Yu-Qing1; Hu, Jiang-Miao1; Huang, Sheng-Zhuo1; Jiang, He-Zhong1; Chen, Zhong-Quan1; Zhou, Jun1; Zhao, You-Xing1, 2
刊名: CHEMISTRY & BIODIVERSITY
关键词: NERVE GROWTH-FACTOR ; RAT ; IDENTIFICATION ; CONSTITUENTS ; RECEPTORS ; JATAMANSI ; CELLS
英文摘要: Two new guaiane-type sesquiterpenoids, valerol A (1) and kessyl 3-acetate (2), together with nine known compounds, valeracetate (3), anismol A (4), orientalol C (5), spatulenol (6), 4 alpha, 10 alpha-epoxyaromadendrane (7), (+)-8-hydroxypinoresinol (8), pinorespiol (9), pinoresinol 4-O-beta-D-glucopyranoside (10), and 8-hydroxypinoresinol 4'-O-beta-D-glucopyranoside (11) were isolated from the roots of Valeriana officinalis. The structures and relative configurations of 1 and 2 were elucidated on the basis of spectroscopic methods (1D- and 2D-NMR, MS, UV, and IR). These compounds were evaluated for inhibitory activity on acetylcholinesterase (AChE) and enhancing activity on nerve growth factor (NGF)-mediated neurite outgrowth in PC12 cells.
出版日期: 2011-10-01
卷号: 8, 期号:10, 页码:1908-1913
语种: 英语
ISSN号: 1612-1872
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/5413
Appears in Collections:植物化学与西部植物资源持续利用国家重点实验室_期刊论文

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作者单位: 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China
2.Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Haikou 571101, Peoples R China
3.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China

Recommended Citation:
Wang, PC; Ran, XH; Chen, R; Luo, HR; Ma, QY; Liu, YQ; Hu, JM; Huang, SZ; Jiang, HZ; Chen, ZQ; Zhou, J; Zhao, YX.Sesquiterpenoids and Lignans from the Roots of Valeriana officinalis L.,CHEMISTRY & BIODIVERSITY,2011,8(10):1908-1913
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