One New Pregnane Glycoside from the Seeds of Cultivated Brucea javanica

doi:10.1007/s12272-011-0809-5

	One New Pregnane Glycoside from the Seeds of Cultivated Brucea javanica
	Liu, Jie-Qing; Wang, Cui-Fang; Li, Xing-Yao; Chen, Jian-Chao; Li, Yan; Qiu, Ming-Hua
通讯作者	Qiu, MH (reprint author), Chinese Acad Sci, State Key Lab Photochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Yunnan, Peoples R China
	2011-08-01
发表期刊	ARCHIVES OF PHARMACAL RESEARCH
ISSN	0253-6269
卷号	34 期号:8 页码:1297-1300
摘要	A new pregnane glycoside, named (20R)-O-(3)-beta-D-glucopyranosyl-(1 -> 2)-alpha-L-arabinopyranosyl-pregn-5-en-3 beta,20-diol (1), and seven known compounds, brusatol (2), bruceine B (3), bruceine D (4), yadanziolide A (5), bruceine E (6), yadanzioside G (7), and yadanzioside B (8), were isolated from the cultivated dry seeds of Brucea jauanica. The structure of 1 was elucidated on the basis of 1D- and 2D-NMR spectroscopic analyses. Their inhibitory effects on tumor cells were also tested. Compound 1 was slightly active against HL-60, SMMC-7721, A-549, and MCF-7 tumor cells. Compounds 2 and 3 demonstrated significant inhibitory activities against all tested cells. These results indicate that cultivated B. jauanica could replace the wild plant as an antitumor plant resource.
关键词	Brucea Javanica Pregnane Glycoside Antitumor Activity Brusatol
学科领域	Pharmacology & Pharmacy
DOI	10.1007/s12272-011-0809-5
收录类别	SCI
语种	英语
WOS记录号	WOS:000294789700011
引用统计	被引频次：13[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/5379
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	Chinese Acad Sci, State Key Lab Photochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Yunnan, Peoples R China
推荐引用方式 GB/T 7714	Liu, Jie-Qing,Wang, Cui-Fang,Li, Xing-Yao,et al. One New Pregnane Glycoside from the Seeds of Cultivated Brucea javanica[J]. ARCHIVES OF PHARMACAL RESEARCH,2011,34(8):1297-1300.
APA	Liu, Jie-Qing,Wang, Cui-Fang,Li, Xing-Yao,Chen, Jian-Chao,Li, Yan,&Qiu, Ming-Hua.(2011).One New Pregnane Glycoside from the Seeds of Cultivated Brucea javanica.ARCHIVES OF PHARMACAL RESEARCH,34(8),1297-1300.
MLA	Liu, Jie-Qing,et al."One New Pregnane Glycoside from the Seeds of Cultivated Brucea javanica".ARCHIVES OF PHARMACAL RESEARCH 34.8(2011):1297-1300.

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