One New Pregnane Glycoside from the Seeds of Cultivated Brucea javanica
Liu, Jie-Qing; Wang, Cui-Fang; Li, Xing-Yao; Chen, Jian-Chao; Li, Yan; Qiu, Ming-Hua
2011-08-01
发表期刊ARCHIVES OF PHARMACAL RESEARCH
ISSN0253-6269
卷号34期号:8页码:1297-1300
摘要A new pregnane glycoside, named (20R)-O-(3)-beta-D-glucopyranosyl-(1 -> 2)-alpha-L-arabinopyranosyl-pregn-5-en-3 beta,20-diol (1), and seven known compounds, brusatol (2), bruceine B (3), bruceine D (4), yadanziolide A (5), bruceine E (6), yadanzioside G (7), and yadanzioside B (8), were isolated from the cultivated dry seeds of Brucea jauanica. The structure of 1 was elucidated on the basis of 1D- and 2D-NMR spectroscopic analyses. Their inhibitory effects on tumor cells were also tested. Compound 1 was slightly active against HL-60, SMMC-7721, A-549, and MCF-7 tumor cells. Compounds 2 and 3 demonstrated significant inhibitory activities against all tested cells. These results indicate that cultivated B. jauanica could replace the wild plant as an antitumor plant resource.
关键词Brucea Javanica Pregnane Glycoside Antitumor Activity Brusatol
资助信息Foundation of State Key Laboratory of Phytochemistry and Plant Resources in West China[P2008-ZZ05, P2010-ZZ14]; CAS[KSCX2-YW-G-038, 027, KSCX2-YW-R-194, 29, KZCX2-XB2-15-03]
收录类别SCI
语种英语
引用统计
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/5379
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位Chinese Acad Sci, State Key Lab Photochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Yunnan, Peoples R China
推荐引用方式
GB/T 7714
Liu, Jie-Qing,Wang, Cui-Fang,Li, Xing-Yao,et al. One New Pregnane Glycoside from the Seeds of Cultivated Brucea javanica[J]. ARCHIVES OF PHARMACAL RESEARCH,2011,34(8):1297-1300.
APA Liu, Jie-Qing,Wang, Cui-Fang,Li, Xing-Yao,Chen, Jian-Chao,Li, Yan,&Qiu, Ming-Hua.(2011).One New Pregnane Glycoside from the Seeds of Cultivated Brucea javanica.ARCHIVES OF PHARMACAL RESEARCH,34(8),1297-1300.
MLA Liu, Jie-Qing,et al."One New Pregnane Glycoside from the Seeds of Cultivated Brucea javanica".ARCHIVES OF PHARMACAL RESEARCH 34.8(2011):1297-1300.
条目包含的文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
201203200013.pdf(418KB) 开放获取--请求全文
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Liu, Jie-Qing]的文章
[Wang, Cui-Fang]的文章
[Li, Xing-Yao]的文章
百度学术
百度学术中相似的文章
[Liu, Jie-Qing]的文章
[Wang, Cui-Fang]的文章
[Li, Xing-Yao]的文章
必应学术
必应学术中相似的文章
[Liu, Jie-Qing]的文章
[Wang, Cui-Fang]的文章
[Li, Xing-Yao]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。