Chemical Constituents from the Aerial Parts of Isodon coetsa and their Cytotoxicity
Zhao, Wei1,2; Pu, Jian Xin1; Du, Xue1; Wu, Ying Li3,4; Zhao, Yong1; He, Fei1; Zhang, Hai Bo1; Xue, Yong Bo1,2; Xiao, Wei Lie1; Chen, Guo Qiang3,4; Sun, Han Dong1
2011-12-01
发表期刊ARCHIVES OF PHARMACAL RESEARCH
ISSN0253-6269
卷号34期号:12页码:2007-2014
摘要Three new compounds (1-3), including a neolignan, a triterpenoid, and a diterpenoid, together with twenty known compounds (4-23), were isolated from the aerial parts of Isodon coetsa. Their structures and relative configurations were elucidated on the basis of spectroscopic data. Compounds 1, 3, 5-9, 11-13, 16-17, and 19-23 were evaluated for their cytotoxicity against HT-29, BEL-7402, and SK-OV-3 human tumor cell lines. Compound 7 showed significant inhibitory effects on all three types of cells, with IC(50) values of 2.52, 3.06, 2.14 mu M, respectively.
关键词Neolignan Triterpenoid Diterpenoid Isodon Coetsa Cytotoxicity Human Tumor Cell Lines
资助信息NSFC-Joint Foundation of Yunnan Province[U0832602]; NSFC[30830119]; Major State Basic Research Development Program of China[2009CB522300, 2009CB940900]; Science and Technology Program of Yunnan Province[2008IF010, 2008CD162]
学科领域Pharmacology & Pharmacy
DOI10.1007/s12272-011-1201-1
收录类别SCI
语种英语
WOS研究方向Pharmacology & Pharmacy
WOS类目Chemistry, Medicinal ; Pharmacology & Pharmacy
WOS记录号WOS:000298341800003
引用统计
被引频次:7[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/5375
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Yunnan, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
3.Shanghai JiaoTong Univ Sch Med SJTU SM Coll, Chinese Minist Educ, Dept Pathophysiol, Shanghai 200025, Peoples R China
4.Shanghai JiaoTong Univ Sch Med SJTU SM Coll, Chinese Minist Educ, Key Lab Cell Differentiat & Apoptosis, Shanghai 200025, Peoples R China
推荐引用方式
GB/T 7714
Zhao, Wei,Pu, Jian Xin,Du, Xue,et al. Chemical Constituents from the Aerial Parts of Isodon coetsa and their Cytotoxicity[J]. ARCHIVES OF PHARMACAL RESEARCH,2011,34(12):2007-2014.
APA Zhao, Wei.,Pu, Jian Xin.,Du, Xue.,Wu, Ying Li.,Zhao, Yong.,...&Sun, Han Dong.(2011).Chemical Constituents from the Aerial Parts of Isodon coetsa and their Cytotoxicity.ARCHIVES OF PHARMACAL RESEARCH,34(12),2007-2014.
MLA Zhao, Wei,et al."Chemical Constituents from the Aerial Parts of Isodon coetsa and their Cytotoxicity".ARCHIVES OF PHARMACAL RESEARCH 34.12(2011):2007-2014.
条目包含的文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
201203200015.pdf(682KB) 开放获取--请求全文
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Zhao, Wei]的文章
[Pu, Jian Xin]的文章
[Du, Xue]的文章
百度学术
百度学术中相似的文章
[Zhao, Wei]的文章
[Pu, Jian Xin]的文章
[Du, Xue]的文章
必应学术
必应学术中相似的文章
[Zhao, Wei]的文章
[Pu, Jian Xin]的文章
[Du, Xue]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。