Chemical Constituents from the Aerial Parts of Isodon coetsa and their Cytotoxicity

doi:10.1007/s12272-011-1201-1

	Chemical Constituents from the Aerial Parts of Isodon coetsa and their Cytotoxicity
	Zhao, Wei 1,2; Pu, Jian Xin 1; Du, Xue 1; Wu, Ying Li 3,4; Zhao, Yong 1; He, Fei 1; Zhang, Hai Bo 1; Xue, Yong Bo 1,2; Xiao, Wei Lie 1; Chen, Guo Qiang 3,4; Sun, Han Dong 1
通讯作者	Pu, JX (reprint author), Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Yunnan, Peoples R China
	2011-12-01
发表期刊	ARCHIVES OF PHARMACAL RESEARCH
ISSN	0253-6269
卷号	34 期号:12 页码:2007-2014
摘要	Three new compounds (1-3), including a neolignan, a triterpenoid, and a diterpenoid, together with twenty known compounds (4-23), were isolated from the aerial parts of Isodon coetsa. Their structures and relative configurations were elucidated on the basis of spectroscopic data. Compounds 1, 3, 5-9, 11-13, 16-17, and 19-23 were evaluated for their cytotoxicity against HT-29, BEL-7402, and SK-OV-3 human tumor cell lines. Compound 7 showed significant inhibitory effects on all three types of cells, with IC(50) values of 2.52, 3.06, 2.14 mu M, respectively.
关键词	Neolignan Triterpenoid Diterpenoid Isodon Coetsa Cytotoxicity Human Tumor Cell Lines
学科领域	Pharmacology & Pharmacy
DOI	10.1007/s12272-011-1201-1
收录类别	SCI
语种	英语
WOS记录号	WOS:000298341800003
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/5375
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Yunnan, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China 3.Shanghai JiaoTong Univ Sch Med SJTU SM Coll, Chinese Minist Educ, Dept Pathophysiol, Shanghai 200025, Peoples R China 4.Shanghai JiaoTong Univ Sch Med SJTU SM Coll, Chinese Minist Educ, Key Lab Cell Differentiat & Apoptosis, Shanghai 200025, Peoples R China
推荐引用方式 GB/T 7714	Zhao, Wei,Pu, Jian Xin,Du, Xue,et al. Chemical Constituents from the Aerial Parts of Isodon coetsa and their Cytotoxicity[J]. ARCHIVES OF PHARMACAL RESEARCH,2011,34(12):2007-2014.
APA	Zhao, Wei.,Pu, Jian Xin.,Du, Xue.,Wu, Ying Li.,Zhao, Yong.,...&Sun, Han Dong.(2011).Chemical Constituents from the Aerial Parts of Isodon coetsa and their Cytotoxicity.ARCHIVES OF PHARMACAL RESEARCH,34(12),2007-2014.
MLA	Zhao, Wei,et al."Chemical Constituents from the Aerial Parts of Isodon coetsa and their Cytotoxicity".ARCHIVES OF PHARMACAL RESEARCH 34.12(2011):2007-2014.

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