Chemical constituents from fruits of Harrisonia perforata
Yan, Xiao-Hui1,2; Di, Ying-Tong1; Fang, Xin1; Yang, Shi-Ying3; He, Hong-Ping1; Li, Shun-Lin1; Lu, Yang3; Hao, Xiao-Jiang1
2011-04-01
发表期刊PHYTOCHEMISTRY
ISSN0031-9422
卷号72期号:6页码:508-513
摘要Eight limonoids (1-8) including three A, B and D-seco-16-nor-type ones, 5,6-dehydrodesepoxyharperforin C2 (1), harrpernoid B (2), and its C-OS epimer, harrpernoid C (3), along with six known compounds (9-14), were isolated from fruits of Harrisonia perforata. Extensive spectroscopic analysis was used to elucidate their structures and stereochemistries. Further confirmation of structures of 1 and 2 were obtained by single-crystal X-ray diffraction. Limonoids (1-8) were evaluated for their anti-tobacco mosaic virus activity and in vitro cytotoxicity against A549 and HL60 cell lines; only compound 2 showed weak activity. (C) 2011 Elsevier Ltd. All rights reserved.
关键词Harrisonia Perforata Simaroubeaceae Limonoids Single-crystal X-ray Diffraction Epimer
资助信息Chinese Academy of Sciences[KSCXR-YW-N-008]; Ministry of Science and Technology[2009CB522300, 2009CB940900]; 863 program or State hightech development plan[2007AA021505]; Yunnan Tobacco company[08A09]
收录类别SCI ; IC
语种英语
引用统计
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/5361
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China
2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China
3.Chinese Acad Sci, Inst Mat Med, Beijing 100050, Peoples R China
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Yan, Xiao-Hui,Di, Ying-Tong,Fang, Xin,et al. Chemical constituents from fruits of Harrisonia perforata[J]. PHYTOCHEMISTRY,2011,72(6):508-513.
APA Yan, Xiao-Hui.,Di, Ying-Tong.,Fang, Xin.,Yang, Shi-Ying.,He, Hong-Ping.,...&Hao, Xiao-Jiang.(2011).Chemical constituents from fruits of Harrisonia perforata.PHYTOCHEMISTRY,72(6),508-513.
MLA Yan, Xiao-Hui,et al."Chemical constituents from fruits of Harrisonia perforata".PHYTOCHEMISTRY 72.6(2011):508-513.
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