A New Megastigmane Diglycoside from Litsea glutinosa (Lour.) C. B. Rob.
Wang, Yun-Song1; Liao, Zhen2; Li, Yan3; Huang, Rong1; Zhang, Hong-Bing1; Yang, Jing-Hua1
2011-11-01
发表期刊JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY
ISSN0103-5053
卷号22期号:11页码:2234-2238
摘要Phytochemical study on the leaves and twigs of afforded the new megastigmane diglycoside (6S, 7E, 9R)-6, 9-dihydroxy-4, 7-megastigmadien-3-one-9-O-[alpha-L-arabinofuranosyl-(1 -> 6)]-beta-D-glucopyranoside (1), along with glycosides (6S, 7E, 9R)-roseoside (2), (7'R, 8'R)-3, 5'-dimethoxy-9, 9'-dihydroxy-4, 7'-epoxylignan 4'-beta-D-glucopyranoside (3), (7'R, 8'S)-dihydrodehydrodiconifenyl alcohol 9'-O-beta-D-xylopyranoside (4) and pinoresinol 3-O-beta-D-glucopyranoside (5). Their structures were established on the basis of extensive spectroscopic and chemical methods. Compounds 2-5 were reported for the first time in this species. Compound 1 was evaluated for cytotoxic activities against human tumor cell lines (myeloid leukemia HL-60, hepatocellular carcinoma SMMC-7721, lung cancer A-549, breast cancer MCF-7 and colon cancer SW480 cells), for which it was proved to be inactive (IC50 > 40 mu M).
关键词Lauraceae Litsea Glutinosa (Lour.) C. B. roB. Megastigmane Glycosides Lignan Glycosides
资助信息National Nature Science Foundation of China[20862018, 21162038]; Science Foundation of Yunnan University[2009B10Q, 2005Z001A]; Science Foundation of Yunnan Province[2006B0003Q, 2007B0006Z, 2007PY01-23]
收录类别SCI ; IC
语种英语
引用统计
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/5319
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Yunnan Univ, Sch Chem Sci & Technol, Minist Educ, Key Lab Med Chem Nat Resource, Kunming 650091, Peoples R China
2.Yunnan Acad Tobacco Sci, Kunming 650031, Peoples R China
3.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China
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Wang, Yun-Song,Liao, Zhen,Li, Yan,et al. A New Megastigmane Diglycoside from Litsea glutinosa (Lour.) C. B. Rob.[J]. JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY,2011,22(11):2234-2238.
APA Wang, Yun-Song,Liao, Zhen,Li, Yan,Huang, Rong,Zhang, Hong-Bing,&Yang, Jing-Hua.(2011).A New Megastigmane Diglycoside from Litsea glutinosa (Lour.) C. B. Rob..JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY,22(11),2234-2238.
MLA Wang, Yun-Song,et al."A New Megastigmane Diglycoside from Litsea glutinosa (Lour.) C. B. Rob.".JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY 22.11(2011):2234-2238.
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