Cytotoxic Amide Alkaloids from Piper boehmeriaefolium
Tang, Gui-Hua1,2; Chen, Dong-Mei3; Qiu, Bei-Ying3; Sheng, Li3; Wang, Yue-Hu1; Hu, Guang-Wan1; Zhao, Fu-Wei1,2; Ma, Li-Juan4; Wang, Huan5; Huang, Qiao-Qin5; Xu, Jin-Jin5; Long, Chun-Lin1; Li, Jia3
2011
发表期刊JOURNAL OF NATURAL PRODUCTS
ISSN0163-3864
卷号74期号:1页码:45-49
摘要Eight new amide alkaloids (1-8) and 19 known ones were isolated from the whole plant of Piper boehmeriaefolium. Their structures were determined through spectroscopic data analyses. Cytotoxic activity of these amides against human cervical carcinoma HeLa cells was evaluated, and 1-[(9E)-10-(3,4-methylenedioxyphenyl)-9-decenoyl]pyrrolidine (9) exhibited significant inhibitory activity with an IC(50) value of 2.7 mu g/mL.
关键词Constituents Nigrum Identification Retrofractum Tuberculatum Alkamides Hispidum Leaves Fruits Larvae
资助信息National Natural Science Foundation of China[20972166, 31070288]; Ministry of Education of China[B08044, MUC 98503-001006]; Chinese Academy of Sciences
学科领域Plant Sciences ; Pharmacology & Pharmacy
DOI10.1021/np100606u
收录类别SCI ; IC
语种英语
WOS研究方向Plant Sciences ; Pharmacology & Pharmacy
WOS类目Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
WOS记录号WOS:000286577800009
引用统计
被引频次:31[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/5239
专题资源植物与生物技术所级重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, Key Lab Econ Plants & Biotechnol, Kunming 650204, Peoples R China
2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China
3.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China
4.Minzu Univ China, Coll Life & Environm Sci, Beijing 100081, Peoples R China
5.Yunnan Agr Univ, Kunming 650201, Peoples R China
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Tang, Gui-Hua,Chen, Dong-Mei,Qiu, Bei-Ying,et al. Cytotoxic Amide Alkaloids from Piper boehmeriaefolium[J]. JOURNAL OF NATURAL PRODUCTS,2011,74(1):45-49.
APA Tang, Gui-Hua.,Chen, Dong-Mei.,Qiu, Bei-Ying.,Sheng, Li.,Wang, Yue-Hu.,...&Li, Jia.(2011).Cytotoxic Amide Alkaloids from Piper boehmeriaefolium.JOURNAL OF NATURAL PRODUCTS,74(1),45-49.
MLA Tang, Gui-Hua,et al."Cytotoxic Amide Alkaloids from Piper boehmeriaefolium".JOURNAL OF NATURAL PRODUCTS 74.1(2011):45-49.
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