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题名: Microbial transformation of diosgenin by filamentous fungus Cunninghamella echinulata
作者: Xiao, Xiao1, 2; Liu, Xi-Kui2; Fu, Shao-Bin1; Sun, Di-An1
刊名: JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
关键词: microbial transformation ; biotransformation ; hydroxylation ; diosgenin Cunninghamella echinulata CGMCC 3 ; 2000
英文摘要: Microbial transformation of diosgenin (1) by suspended-cell cultures of the filamentous fungus Cunninghamella echinulata CGMCC 3.2000 was investigated. Incubation of the substrate diosgenin (1) with this fungus led to the isolation of three products: two known compounds, (25R)-spirost-5-en-3,7,12-triol (2) and (25R)-spirost-5-en-3,7,11-triol (3), and a new compound (25R)-spirost-5-en-3,7,11-triol (4). The structural elucidations of the three compounds were achieved mainly by the MS, 1D and 2D NMR spectroscopic methods and comparison with known compounds. C. echinulata CGMCC 3.2000 has not been used before in the biotransformation of diosgenin (1).
出版日期: 2011
卷号: 13, 期号:3, 页码:270-275
DOI标识: 10.1080/10286020.2010.551117
语种: 英语
ISSN号: 1028-6020
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内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/5233
Appears in Collections:资源植物与生物技术所级重点实验室_期刊论文

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作者单位: 1.Chinese Acad Med Sci, Peking Union Med Coll, Inst Med Plant Dev, Beijing 100193, Peoples R China
2.Chinese Acad Sci, Kunming Inst Bot, Kunming 650204, Peoples R China

Recommended Citation:
Xiao, X; Liu, XK; Fu, SB; Sun, DA.Microbial transformation of diosgenin by filamentous fungus Cunninghamella echinulata,JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,2011,13(3):270-275
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