| Microbial transformation of diosgenin by filamentous fungus Cunninghamella echinulata | |
| Xiao, Xiao1,2; Liu, Xi-Kui2; Fu, Shao-Bin1; Sun, Di-An1 | |
| 通讯作者 | Sun, DA (reprint author), Chinese Acad Med Sci, Peking Union Med Coll, Inst Med Plant Dev, Beijing 100193, Peoples R China |
| 2011 | |
| 发表期刊 | JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
 |
| ISSN | 1028-6020 |
| 卷号 | 13期号:3页码:270-275 |
| 摘要 | Microbial transformation of diosgenin (1) by suspended-cell cultures of the filamentous fungus Cunninghamella echinulata CGMCC 3.2000 was investigated. Incubation of the substrate diosgenin (1) with this fungus led to the isolation of three products: two known compounds, (25R)-spirost-5-en-3,7,12-triol (2) and (25R)-spirost-5-en-3,7,11-triol (3), and a new compound (25R)-spirost-5-en-3,7,11-triol (4). The structural elucidations of the three compounds were achieved mainly by the MS, 1D and 2D NMR spectroscopic methods and comparison with known compounds. C. echinulata CGMCC 3.2000 has not been used before in the biotransformation of diosgenin (1). |
| 关键词 | Microbial Transformation Biotransformation Hydroxylation Diosgenin Cunninghamella Echinulata Cgmcc 3 2000 |
| 学科领域 | Plant Sciences ; Chemistry ; Pharmacology & Pharmacy |
| DOI | 10.1080/10286020.2010.551117 |
| 收录类别 | SCI ; IC |
| 语种 | 英语 |
| WOS记录号 | WOS:000288674400013 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kib.ac.cn/handle/151853/5233 |
| 专题 | 资源植物与生物技术所级重点实验室 |
| 作者单位 | 1.Chinese Acad Med Sci, Peking Union Med Coll, Inst Med Plant Dev, Beijing 100193, Peoples R China 2.Chinese Acad Sci, Kunming Inst Bot, Kunming 650204, Peoples R China |
| 推荐引用方式 GB/T 7714 | Xiao, Xiao,Liu, Xi-Kui,Fu, Shao-Bin,et al. Microbial transformation of diosgenin by filamentous fungus Cunninghamella echinulata[J]. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,2011,13(3):270-275. |
| APA | Xiao, Xiao,Liu, Xi-Kui,Fu, Shao-Bin,&Sun, Di-An.(2011).Microbial transformation of diosgenin by filamentous fungus Cunninghamella echinulata.JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,13(3),270-275. |
| MLA | Xiao, Xiao,et al."Microbial transformation of diosgenin by filamentous fungus Cunninghamella echinulata".JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH 13.3(2011):270-275. |
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