| Carboxymethyl Flavonoids and A Monoterpene Glucoside from Selaginella moellendorffii | |
Wang, Hong-Sheng2,3; Sun, Ling4; Wang, Yue-Hu2 ; Shi, Ya-Na2; Tang, Gui-Hua2; Zhao, Fu-Wei2; Niu, Hong-Mei2; Long, Chun-Lin1,2; Li, Ling4
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| Corresponding Author | Long, CL (reprint author), Minzu Univ China, Coll Life & Environm Sci, Beijing 100081, Peoples R China |
| 2011-08-01 | |
| Source Publication | ARCHIVES OF PHARMACAL RESEARCH
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| ISSN | 0253-6269 |
| Volume | 34Issue:8Pages:1283-1288 |
| Abstract | A new dihydroflavone, 5-carboxymethyl-7,4'-dihydroxyflavonone (1), and its glucoside 5carboxymethyl-7,4'-dihydroxyflavonone-7-O-beta-D-glucopyranoside (2), and one new monoterpene glucoside, (4Z,6E)-2,7-dimethyl-8-hydroxyocta-4,6-dienoic acid 8-O-beta-D-glucopyranoside (3), were isolated from the whole plants of Selaginella moellendorffii. Their structures were determined by spectroscopic methods and chemical transformation. Compound 2 was evaluated for the ability to enhance glucose consumption in normal and insulin-resistant L6 muscle cells induced by high concentrations of insulin and glucose. Glucose consumption in insulin-resistant cells (but not in normal cells) was increased 15.2 +/- 3.3% (p < 0.01) by compound 2 at a concentration of 0.1 mu M in the presence of insulin (1 nM). |
| Keyword | Selaginellaceae Selaginella Moellendorffii Flavonoids Monoterpene Glucoside Insulin-resistance |
| Subject Area | Pharmacology & Pharmacy |
| DOI | 10.1007/s12272-011-0807-7 |
| Indexed By | SCI |
| Language | 英语 |
| WOS ID | WOS:000294789700009 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.kib.ac.cn/handle/151853/5217 |
| Collection | 资源植物与生物技术所级重点实验室 |
| Affiliation | 1.Minzu Univ China, Coll Life & Environm Sci, Beijing 100081, Peoples R China 2.Chinese Acad Sci, Key Lab Econ Plants & Biotechnol, Kunming Inst Bot, Kunming 650201, Peoples R China 3.Henan Inst Sci & Technol, Xinxiang 453003, Peoples R China 4.Kunming Med Univ, Yunnan Key Lab Pharmacol Nat Prod, Kunming 650500, Peoples R China |
| Recommended Citation GB/T 7714 | Wang, Hong-Sheng,Sun, Ling,Wang, Yue-Hu,et al. Carboxymethyl Flavonoids and A Monoterpene Glucoside from Selaginella moellendorffii[J]. ARCHIVES OF PHARMACAL RESEARCH,2011,34(8):1283-1288. |
| APA | Wang, Hong-Sheng.,Sun, Ling.,Wang, Yue-Hu.,Shi, Ya-Na.,Tang, Gui-Hua.,...&Li, Ling.(2011).Carboxymethyl Flavonoids and A Monoterpene Glucoside from Selaginella moellendorffii.ARCHIVES OF PHARMACAL RESEARCH,34(8),1283-1288. |
| MLA | Wang, Hong-Sheng,et al."Carboxymethyl Flavonoids and A Monoterpene Glucoside from Selaginella moellendorffii".ARCHIVES OF PHARMACAL RESEARCH 34.8(2011):1283-1288. |
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