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题名: Carboxymethyl Flavonoids and A Monoterpene Glucoside from Selaginella moellendorffii
作者: Wang, Hong-Sheng2, 3; Sun, Ling4; Wang, Yue-Hu2; Shi, Ya-Na2; Tang, Gui-Hua2; Zhao, Fu-Wei2; Niu, Hong-Mei2; Long, Chun-Lin1, 2; Li, Ling4
刊名: ARCHIVES OF PHARMACAL RESEARCH
关键词: Selaginellaceae ; Selaginella moellendorffii ; Flavonoids ; Monoterpene glucoside ; Insulin-resistance
英文摘要: A new dihydroflavone, 5-carboxymethyl-7,4'-dihydroxyflavonone (1), and its glucoside 5carboxymethyl-7,4'-dihydroxyflavonone-7-O-beta-D-glucopyranoside (2), and one new monoterpene glucoside, (4Z,6E)-2,7-dimethyl-8-hydroxyocta-4,6-dienoic acid 8-O-beta-D-glucopyranoside (3), were isolated from the whole plants of Selaginella moellendorffii. Their structures were determined by spectroscopic methods and chemical transformation. Compound 2 was evaluated for the ability to enhance glucose consumption in normal and insulin-resistant L6 muscle cells induced by high concentrations of insulin and glucose. Glucose consumption in insulin-resistant cells (but not in normal cells) was increased 15.2 +/- 3.3% (p < 0.01) by compound 2 at a concentration of 0.1 mu M in the presence of insulin (1 nM).
出版日期: 2011-08-01
卷号: 34, 期号:8, 页码:1283-1288
DOI标识: 10.1007/s12272-011-0807-7
语种: 英语
ISSN号: 0253-6269
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/5217
Appears in Collections:资源植物与生物技术所级重点实验室_期刊论文

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作者单位: 1.Minzu Univ China, Coll Life & Environm Sci, Beijing 100081, Peoples R China
2.Chinese Acad Sci, Key Lab Econ Plants & Biotechnol, Kunming Inst Bot, Kunming 650201, Peoples R China
3.Henan Inst Sci & Technol, Xinxiang 453003, Peoples R China
4.Kunming Med Univ, Yunnan Key Lab Pharmacol Nat Prod, Kunming 650500, Peoples R China

Recommended Citation:
Wang, HS; Sun, L; Wang, YH; Shi, YN; Tang, GH; Zhao, FW; Niu, HM; Long, CL; Li, L.Carboxymethyl Flavonoids and A Monoterpene Glucoside from Selaginella moellendorffii,ARCHIVES OF PHARMACAL RESEARCH,2011,34(8):1283-1288
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