Components of stem barks of Winchia calophylla A. DC. and their bronchodilator activities

	Components of stem barks of Winchia calophylla A. DC. and their bronchodilator activities
	Zhu, WM ; He, HP ; Fan, LM ; Shen, YM ; Zhou, J; Hao, XJ
	2005-07-01
发表期刊	JOURNAL OF INTEGRATIVE PLANT BIOLOGY
卷号	47 期号:7 页码:892-896
摘要	The Dai medicinal plant Winchia calophylla A. DC. (Apocynaceae) has efficacy as an anti-cough and anti-asthmatic medication. In order to investigate its relative bioactive components, we studied the chemical constituents of this plant. Using repeated column chromatography, 28 compounds, including loganin, six phenolic compounds, 17 indole alkaloids, three pyridine alkaloids, and a quinoline alkaloid, were isolated from the stem barks of W. calophylla. Loganin, paeonol, N (4)-methyl akuammicine, and cantleyine exhibited a moderate relaxation effect on isolated smooth muscles of guinea-pig tracheal spirals and lung strips and may be the bioactive components responsible for the bronchodilation produced by W. calophylla.
关键词	Alkaloid Apocynaceae Bronchodilatation Winchia Calophylla
学科领域	Biochemistry & Molecular Biology ; Plant Sciences
收录类别	SCI
语种	英语
WOS记录号	WOS:000230290500014
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/5148
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources, Kunming 650204, Peoples R China 2.Ocean Univ China, Marine Drug & Food Inst, Key Lab Marine Drugs Shandong Prov, Minist Educ, Qingdao 266003, Peoples R China 3.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
推荐引用方式 GB/T 7714	Zhu, WM,He, HP,Fan, LM,et al. Components of stem barks of Winchia calophylla A. DC. and their bronchodilator activities[J]. JOURNAL OF INTEGRATIVE PLANT BIOLOGY,2005,47(7):892-896.
APA	Zhu, WM,He, HP,Fan, LM,Shen, YM,Zhou, J,&Hao, XJ.(2005).Components of stem barks of Winchia calophylla A. DC. and their bronchodilator activities.JOURNAL OF INTEGRATIVE PLANT BIOLOGY,47(7),892-896.
MLA	Zhu, WM,et al."Components of stem barks of Winchia calophylla A. DC. and their bronchodilator activities".JOURNAL OF INTEGRATIVE PLANT BIOLOGY 47.7(2005):892-896.

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