Components of stem barks of Winchia calophylla A. DC. and their bronchodilator activities
Zhu, WM; He, HP; Fan, LM; Shen, YM; Zhou, J; Hao, XJ
2005-07-01
发表期刊JOURNAL OF INTEGRATIVE PLANT BIOLOGY
卷号47期号:7页码:892-896
摘要The Dai medicinal plant Winchia calophylla A. DC. (Apocynaceae) has efficacy as an anti-cough and anti-asthmatic medication. In order to investigate its relative bioactive components, we studied the chemical constituents of this plant. Using repeated column chromatography, 28 compounds, including loganin, six phenolic compounds, 17 indole alkaloids, three pyridine alkaloids, and a quinoline alkaloid, were isolated from the stem barks of W. calophylla. Loganin, paeonol, N (4)-methyl akuammicine, and cantleyine exhibited a moderate relaxation effect on isolated smooth muscles of guinea-pig tracheal spirals and lung strips and may be the bioactive components responsible for the bronchodilation produced by W. calophylla.
关键词Alkaloid Apocynaceae Bronchodilatation Winchia Calophylla
学科领域Biochemistry & Molecular Biology ; Plant Sciences
收录类别SCI
语种英语
WOS研究方向Biochemistry & Molecular Biology ; Plant Sciences
WOS类目Biochemistry & Molecular Biology ; Plant Sciences
WOS记录号WOS:000230290500014
引用统计
被引频次:13[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/5148
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources, Kunming 650204, Peoples R China
2.Ocean Univ China, Marine Drug & Food Inst, Key Lab Marine Drugs Shandong Prov, Minist Educ, Qingdao 266003, Peoples R China
3.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
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Zhu, WM,He, HP,Fan, LM,et al. Components of stem barks of Winchia calophylla A. DC. and their bronchodilator activities[J]. JOURNAL OF INTEGRATIVE PLANT BIOLOGY,2005,47(7):892-896.
APA Zhu, WM,He, HP,Fan, LM,Shen, YM,Zhou, J,&Hao, XJ.(2005).Components of stem barks of Winchia calophylla A. DC. and their bronchodilator activities.JOURNAL OF INTEGRATIVE PLANT BIOLOGY,47(7),892-896.
MLA Zhu, WM,et al."Components of stem barks of Winchia calophylla A. DC. and their bronchodilator activities".JOURNAL OF INTEGRATIVE PLANT BIOLOGY 47.7(2005):892-896.
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