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题名: Lanostane-type triterpenoids from Kadsura coccinea
作者: Hu, Zheng-Xi1, 2; Li, Xiao-Nian2, 3; Shi, Yi-Ming2, 3; Wang, Wei-Guang2, 3; Du, Xue2, 3; null(李艳)2, 3; Zhang, Yong-Hui1; Pu, Jian-Xin2, 3; Sun, Han-Dong2, 3
刊名: TETRAHEDRON
关键词: Kadsura coccinea ; Lanostane-type triterpenoids ; Cytotoxicity
英文摘要: Systematic phytochemical investigation on the stems of Kadsura coccinea resulted in the isolation of eleven new lanostane-type triterpenoids, named kadcoccinones G-Q (1-11), together with two known structural analogues, kadpolysperin M (12) and abiesatrine D (13). Their structures were characterized on the basis of comprehensive spectroscopic methods, and the absolute configuration of 1 was ascertained by single-crystal X-ray diffraction. Structurally, compounds 1/2, 4/5, and 6/7 were three pairs of C-12 epimers, respectively. Additionally, compounds 1-11 were evaluated for their in vitro cytotoxicity against the human tumor HL-60, SMMC-772, A-549, MCF-7, SW-480, and HeLa cell lines using the MTS viability assay. (C) 2017 Elsevier Ltd. All rights reserved.
出版日期: 2017-05-18
卷号: 73, 期号:20, 页码:2931-2937
DOI标识: 10.1016/j.tet.2017.03.087
语种: 英语
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内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/51235
Appears in Collections:植物化学与西部植物资源持续利用国家重点实验室_期刊论文

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作者单位: 1.Huazhong Univ Sci & Technol, Tongji Med Coll, Sch Pharm, Hubei Key Lab Nat Med Chem & Resource Evaluat, Wuhan 430030, Peoples R China
2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China
3.Chinese Acad Sci, Kunming Inst Bot, Yunnan Key Lab Nat Med Chem, Kunming 650201, Peoples R China

Recommended Citation:
Hu, Zheng-Xi,Li, Xiao-Nian,Shi, Yi-Ming,et al. Lanostane-type triterpenoids from Kadsura coccinea[J]. TETRAHEDRON,2017,73(20):2931-2937.
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