| Lanostane-type triterpenoids from Kadsura coccinea | |
Hu, Zheng-Xi1,2; Li, Xiao-Nian2,3; Shi, Yi-Ming2,3 ; Wang, Wei-Guang2,3; Du, Xue2,3; Li, Yan2,3; Zhang, Yong-Hui1; Pu, Jian-Xin2,3; Sun, Han-Dong2,3
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| 2017-05-18 | |
| Source Publication | TETRAHEDRON
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| Volume | 73Issue:20Pages:2931-2937 |
| Abstract | Systematic phytochemical investigation on the stems of Kadsura coccinea resulted in the isolation of eleven new lanostane-type triterpenoids, named kadcoccinones G-Q (1-11), together with two known structural analogues, kadpolysperin M (12) and abiesatrine D (13). Their structures were characterized on the basis of comprehensive spectroscopic methods, and the absolute configuration of 1 was ascertained by single-crystal X-ray diffraction. Structurally, compounds 1/2, 4/5, and 6/7 were three pairs of C-12 epimers, respectively. Additionally, compounds 1-11 were evaluated for their in vitro cytotoxicity against the human tumor HL-60, SMMC-772, A-549, MCF-7, SW-480, and HeLa cell lines using the MTS viability assay. (C) 2017 Elsevier Ltd. All rights reserved. |
| Keyword | Kadsura Coccinea Lanostane-type Triterpenoids Cytotoxicity |
| DOI | 10.1016/j.tet.2017.03.087 |
| Indexed By | SCI |
| Language | 英语 |
| WOS ID | WOS:000401210200010 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.kib.ac.cn/handle/151853/51235 |
| Collection | 植物化学与西部植物资源持续利用国家重点实验室 |
| Affiliation | 1.Huazhong Univ Sci & Technol, Tongji Med Coll, Sch Pharm, Hubei Key Lab Nat Med Chem & Resource Evaluat, Wuhan 430030, Peoples R China 2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China 3.Chinese Acad Sci, Kunming Inst Bot, Yunnan Key Lab Nat Med Chem, Kunming 650201, Peoples R China |
| Recommended Citation GB/T 7714 | Hu, Zheng-Xi,Li, Xiao-Nian,Shi, Yi-Ming,et al. Lanostane-type triterpenoids from Kadsura coccinea[J]. TETRAHEDRON,2017,73(20):2931-2937. |
| APA | Hu, Zheng-Xi.,Li, Xiao-Nian.,Shi, Yi-Ming.,Wang, Wei-Guang.,Du, Xue.,...&Sun, Han-Dong.(2017).Lanostane-type triterpenoids from Kadsura coccinea.TETRAHEDRON,73(20),2931-2937. |
| MLA | Hu, Zheng-Xi,et al."Lanostane-type triterpenoids from Kadsura coccinea".TETRAHEDRON 73.20(2017):2931-2937. |
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| File Name/Size | DocType | Version | Access | License | ||
| 1-s2.0-S004040201730（860KB） | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | View Application Full Text | |
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