Lanostane-type triterpenoids from Kadsura coccinea | |
Hu, Zheng-Xi1,2; Li, Xiao-Nian2,3; Shi, Yi-Ming2,3![]() ![]() ![]() ![]() | |
2017-05-18 | |
Source Publication | TETRAHEDRON
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Volume | 73Issue:20Pages:2931-2937 |
Abstract | Systematic phytochemical investigation on the stems of Kadsura coccinea resulted in the isolation of eleven new lanostane-type triterpenoids, named kadcoccinones G-Q (1-11), together with two known structural analogues, kadpolysperin M (12) and abiesatrine D (13). Their structures were characterized on the basis of comprehensive spectroscopic methods, and the absolute configuration of 1 was ascertained by single-crystal X-ray diffraction. Structurally, compounds 1/2, 4/5, and 6/7 were three pairs of C-12 epimers, respectively. Additionally, compounds 1-11 were evaluated for their in vitro cytotoxicity against the human tumor HL-60, SMMC-772, A-549, MCF-7, SW-480, and HeLa cell lines using the MTS viability assay. (C) 2017 Elsevier Ltd. All rights reserved. |
Keyword | Kadsura Coccinea Lanostane-type Triterpenoids Cytotoxicity |
DOI | 10.1016/j.tet.2017.03.087 |
Indexed By | SCI |
Language | 英语 |
WOS ID | WOS:000401210200010 |
Citation statistics | |
Document Type | 期刊论文 |
Identifier | http://ir.kib.ac.cn/handle/151853/51235 |
Collection | 植物化学与西部植物资源持续利用国家重点实验室 |
Affiliation | 1.Huazhong Univ Sci & Technol, Tongji Med Coll, Sch Pharm, Hubei Key Lab Nat Med Chem & Resource Evaluat, Wuhan 430030, Peoples R China 2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China 3.Chinese Acad Sci, Kunming Inst Bot, Yunnan Key Lab Nat Med Chem, Kunming 650201, Peoples R China |
Recommended Citation GB/T 7714 | Hu, Zheng-Xi,Li, Xiao-Nian,Shi, Yi-Ming,et al. Lanostane-type triterpenoids from Kadsura coccinea[J]. TETRAHEDRON,2017,73(20):2931-2937. |
APA | Hu, Zheng-Xi.,Li, Xiao-Nian.,Shi, Yi-Ming.,Wang, Wei-Guang.,Du, Xue.,...&Sun, Han-Dong.(2017).Lanostane-type triterpenoids from Kadsura coccinea.TETRAHEDRON,73(20),2931-2937. |
MLA | Hu, Zheng-Xi,et al."Lanostane-type triterpenoids from Kadsura coccinea".TETRAHEDRON 73.20(2017):2931-2937. |
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