Lanostane-type triterpenoids from Kadsura coccinea
Hu, Zheng-Xi1,2; Li, Xiao-Nian2,3; Shi, Yi-Ming2,3; Wang, Wei-Guang2,3; Du, Xue2,3; Li, Yan2,3; Zhang, Yong-Hui1; Pu, Jian-Xin2,3; Sun, Han-Dong2,3
Source PublicationTETRAHEDRON
AbstractSystematic phytochemical investigation on the stems of Kadsura coccinea resulted in the isolation of eleven new lanostane-type triterpenoids, named kadcoccinones G-Q (1-11), together with two known structural analogues, kadpolysperin M (12) and abiesatrine D (13). Their structures were characterized on the basis of comprehensive spectroscopic methods, and the absolute configuration of 1 was ascertained by single-crystal X-ray diffraction. Structurally, compounds 1/2, 4/5, and 6/7 were three pairs of C-12 epimers, respectively. Additionally, compounds 1-11 were evaluated for their in vitro cytotoxicity against the human tumor HL-60, SMMC-772, A-549, MCF-7, SW-480, and HeLa cell lines using the MTS viability assay. (C) 2017 Elsevier Ltd. All rights reserved.
KeywordKadsura Coccinea Lanostane-type Triterpenoids Cytotoxicity
Indexed BySCI
WOS IDWOS:000401210200010
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Document Type期刊论文
Affiliation1.Huazhong Univ Sci & Technol, Tongji Med Coll, Sch Pharm, Hubei Key Lab Nat Med Chem & Resource Evaluat, Wuhan 430030, Peoples R China
2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China
3.Chinese Acad Sci, Kunming Inst Bot, Yunnan Key Lab Nat Med Chem, Kunming 650201, Peoples R China
Recommended Citation
GB/T 7714
Hu, Zheng-Xi,Li, Xiao-Nian,Shi, Yi-Ming,et al. Lanostane-type triterpenoids from Kadsura coccinea[J]. TETRAHEDRON,2017,73(20):2931-2937.
APA Hu, Zheng-Xi.,Li, Xiao-Nian.,Shi, Yi-Ming.,Wang, Wei-Guang.,Du, Xue.,...&Sun, Han-Dong.(2017).Lanostane-type triterpenoids from Kadsura coccinea.TETRAHEDRON,73(20),2931-2937.
MLA Hu, Zheng-Xi,et al."Lanostane-type triterpenoids from Kadsura coccinea".TETRAHEDRON 73.20(2017):2931-2937.
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