The chemistry and biochemistry of Spiraea japonica complex
Hao, XJ; Shen, YM; Li, L; He, HP
2003-11-01
发表期刊CURRENT MEDICINAL CHEMISTRY
卷号10期号:21页码:2253-2263
摘要The characteristic components of Spiraea japonica complex, which consists of seven varieties, are the hetisine- and atisine-type diterpene alkaloids, and the atisane-type diterpenes. From this complex, 20 hetisines, 37 atisines and 7 diterpenes were isolated during 1964-2001, including the observations of the isomerization of spiraea diterpene alkaloids having the oxazolidine ring and the interconversion of the oxazolidine rings, the configuration of the oxygen substitution at C-15 of the atisine-type alkaloids, and the interconversion relationship between the two main subtypes of the hetisine-type alkaloids. The chemotaxonomy based on structures of the reported diterpene alkaloids were suggested. The studies on the anti-inflammation, anti-platelet aggregation and neuroprotective bioactivities of the alkaloids from S japonica var. acuta were reviewed as well.
关键词Spiraea Japonica Chemotaxonomy Hetisine Atisine Atisane Diterpenes Diterpene Alkaloids Anti-inflammation Anti-platelet Aggregation Neuroprotection
学科领域Biochemistry & Molecular Biology ; Chemistry, Medicinal ; Pharmacology & Pharmacy
收录类别ISTP ; SCI
语种英语
WOS记录号WOS:000185946900004
引用统计
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/5082
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Yunnan, Peoples R China
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Hao, XJ,Shen, YM,Li, L,et al. The chemistry and biochemistry of Spiraea japonica complex[J]. CURRENT MEDICINAL CHEMISTRY,2003,10(21):2253-2263.
APA Hao, XJ,Shen, YM,Li, L,&He, HP.(2003).The chemistry and biochemistry of Spiraea japonica complex.CURRENT MEDICINAL CHEMISTRY,10(21),2253-2263.
MLA Hao, XJ,et al."The chemistry and biochemistry of Spiraea japonica complex".CURRENT MEDICINAL CHEMISTRY 10.21(2003):2253-2263.
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