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题名: The chemistry and biochemistry of Spiraea japonica complex
作者: null(郝小江); Shen, YM; Li, L; He, HP
刊名: CURRENT MEDICINAL CHEMISTRY
关键词: Spiraea japonica ; chemotaxonomy ; hetisine ; atisine ; atisane ; diterpenes ; diterpene alkaloids ; anti-inflammation ; anti-platelet aggregation ; neuroprotection
英文摘要: The characteristic components of Spiraea japonica complex, which consists of seven varieties, are the hetisine- and atisine-type diterpene alkaloids, and the atisane-type diterpenes. From this complex, 20 hetisines, 37 atisines and 7 diterpenes were isolated during 1964-2001, including the observations of the isomerization of spiraea diterpene alkaloids having the oxazolidine ring and the interconversion of the oxazolidine rings, the configuration of the oxygen substitution at C-15 of the atisine-type alkaloids, and the interconversion relationship between the two main subtypes of the hetisine-type alkaloids. The chemotaxonomy based on structures of the reported diterpene alkaloids were suggested. The studies on the anti-inflammation, anti-platelet aggregation and neuroprotective bioactivities of the alkaloids from S japonica var. acuta were reviewed as well.
出版日期: 2003-11-01
卷号: 10, 期号:21, 页码:2253-2263
语种: 英语
收录类别: ISTP ; SCI
学科分类: Biochemistry & Molecular Biology; Chemistry, Medicinal; Pharmacology & Pharmacy
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内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/5082
Appears in Collections:植物化学与西部植物资源持续利用国家重点实验室_期刊论文

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作者单位: 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Yunnan, Peoples R China

Recommended Citation:
Hao, XJ; Shen, YM; Li, L; He, HP.The chemistry and biochemistry of Spiraea japonica complex,CURRENT MEDICINAL CHEMISTRY,2003,10(21):2253-2263
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