|The chemistry and biochemistry of Spiraea japonica complex|
|Hao, XJ; Shen, YM; Li, L; He, HP
|发表期刊||CURRENT MEDICINAL CHEMISTRY
|摘要||The characteristic components of Spiraea japonica complex, which consists of seven varieties, are the hetisine- and atisine-type diterpene alkaloids, and the atisane-type diterpenes. From this complex, 20 hetisines, 37 atisines and 7 diterpenes were isolated during 1964-2001, including the observations of the isomerization of spiraea diterpene alkaloids having the oxazolidine ring and the interconversion of the oxazolidine rings, the configuration of the oxygen substitution at C-15 of the atisine-type alkaloids, and the interconversion relationship between the two main subtypes of the hetisine-type alkaloids. The chemotaxonomy based on structures of the reported diterpene alkaloids were suggested. The studies on the anti-inflammation, anti-platelet aggregation and neuroprotective bioactivities of the alkaloids from S japonica var. acuta were reviewed as well.|
|作者单位||Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Yunnan, Peoples R China|
Hao, XJ,Shen, YM,Li, L,et al. The chemistry and biochemistry of Spiraea japonica complex[J]. CURRENT MEDICINAL CHEMISTRY,2003,10(21):2253-2263.
Hao, XJ,Shen, YM,Li, L,&He, HP.(2003).The chemistry and biochemistry of Spiraea japonica complex.CURRENT MEDICINAL CHEMISTRY,10(21),2253-2263.
Hao, XJ,et al."The chemistry and biochemistry of Spiraea japonica complex".CURRENT MEDICINAL CHEMISTRY 10.21(2003):2253-2263.