| A petrol ether extract of the roots of Onosma paniculatum induces cell death in a caspase dependent manner | |
Rinner, Beate2; Kretschmer, Nadine1; Knausz, Heike2; Mayer, Andrea2; Boechzelt, Herbert3; Hao, Xiao-Jiang4 ; Heubl, Guenther5; Efferth, Thomas6; Schaider, Helmut7,8; Bauer, Rudolf1
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| 通讯作者 | Bauer, R, Karl Franzens Univ Graz, Dept Pharmacognosy, Inst Pharmaceut Sci, Univ Pl 4, A-8010 Graz, Austria |
| 2010-05-27 | |
| 发表期刊 | JOURNAL OF ETHNOPHARMACOLOGY
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| ISSN | 0378-8741 |
| 卷号 | 129期号:2页码:182-188 |
| 摘要 | Aim of the study: Traditional Chinese medicine (TCM) has become very popular in Western countries during the last years. Zicao, a remedy of TCM, has been traditionally used to treat cancer, and, its main constituents, naphthoquinones, have been reported to possess antitumor activity (Chen et al., 2002; Papageorgiou et al., 1999). Here, we prepared extracts of different polarities of Onosma paniculatum Bur. & Franch., a plant which is amongst others used as Zicao, but, much less investigated. The extracts were analyzed concerning their growth inhibitory and apoptosis-inducing activity in various tumor cells. |
| 关键词 | Onosma Paniculatum Zicao Cancer Cell Cycle Caspase-3 |
| 学科领域 | Plant Sciences ; Chemistry, Medicinal ; Integrative & Complementary Medicine ; Pharmacology & Pharmacy |
| DOI | 10.1016/j.jep.2010.02.006 |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000278651300005 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kib.ac.cn/handle/151853/4916 |
| 专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Karl Franzens Univ Graz, Dept Pharmacognosy, Inst Pharmaceut Sci, A-8010 Graz, Austria 2.Med Univ Graz, Core Facil Flow Cytometry, Med Res Ctr, A-8010 Graz, Austria 3.Joanneum Res Forsch Gesell mbH, A-8010 Graz, Austria 4.Chinese Acad Sci, Kunming Inst Bot, Kunming 650204, Yunnan, Peoples R China 5.LMU Dept Biol Systemat Bot & Mykol, D-80638 Munich, Germany 6.Johannes Gutenberg Univ Mainz, Dept Pharmaceut Biol, Inst Pharm, D-55099 Mainz, Germany 7.Med Univ Graz, Dept Dermatol, Canc Biol Unit, A-8036 Graz, Austria 8.Med Univ Graz, Med Res Ctr, A-8036 Graz, Austria |
| 推荐引用方式 GB/T 7714 | Rinner, Beate,Kretschmer, Nadine,Knausz, Heike,et al. A petrol ether extract of the roots of Onosma paniculatum induces cell death in a caspase dependent manner[J]. JOURNAL OF ETHNOPHARMACOLOGY,2010,129(2):182-188. |
| APA | Rinner, Beate.,Kretschmer, Nadine.,Knausz, Heike.,Mayer, Andrea.,Boechzelt, Herbert.,...&Bauer, Rudolf.(2010).A petrol ether extract of the roots of Onosma paniculatum induces cell death in a caspase dependent manner.JOURNAL OF ETHNOPHARMACOLOGY,129(2),182-188. |
| MLA | Rinner, Beate,et al."A petrol ether extract of the roots of Onosma paniculatum induces cell death in a caspase dependent manner".JOURNAL OF ETHNOPHARMACOLOGY 129.2(2010):182-188. |
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