Selaginellins G (1) and H (2), two new selaginellin derivatives, were isolated from the whole plant of Selaginella pulvinata. Their structures were elucidated, and complete assignments of the (1)H and (13)C NMR spectroscopic data were achieved by 1D and 2D NMR experiments (HSQC, HMBC, COSY and ROESY). Compound 1 displayed good antifungal activity against Candida albicans with an IC(50) value of 5.3 mu g/ml. Copyright (C) 2010 John Wiley & Sons, Ltd.
1.China Pharmaceut Univ, Dept Chinese Mat Med Anal, Nanjing 210009, Peoples R China 2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China 3.Jiangsu Prov Inst Mat Med, Nanjing 210009, Peoples R China
Recommended Citation:
Cao, YA; Chen, JJ; Tan, NH; Wu, YP; Yang, J; Wang, QA.Structure determination of selaginellins G and H from Selaginella pulvinata by NMR spectroscopy,MAGNETIC RESONANCE IN CHEMISTRY,2010,48(8):656-659