| Antimicrobial Activity of Sphingolipids Isolated from the Stems of Cucumber (Cucumis sativus L.) | |
Tang, Jing1,2; Meng, Xiangjie1; Liu, Hao1; Zhao, Jianglin1; Zhou, Ligang1; Qiu, Minghua2 ; Zhang, Xianming2; Yu, Zhu3; Yang, Fuyu3
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| 2010-12-01 | |
| 发表期刊 | MOLECULES
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| ISSN | 1420-3049 |
| 卷号 | 15期号:12页码:9288-9297 |
| 摘要 | Three antimicrobial sphingolipids were separated by bioassay-guided isolation from the chloroform fraction of the crude methanol extract of cucumber (Cucumis sativus L.) stems and identified as (2S,3S,4R,10E)-2-[(2'R)-2-hydroxytetra-cosanoylamino]-1,3,4-octadecanetriol-10-ene (1), 1-O-beta-D-glucopyranosyl(2S,3S,4R,10E)-2-[(2'R)-2-hydroxytetracosanoylamino]-1,3,4-octadecanetriol-10-ene (2) and soya-cerebroside I (3) by their physicochemical properties and spectroscopic analysis. They were evaluated to show antifungal and antibacterial activity on test microorganisms including four fungal and three bacterial species. Among them, compound 1, a relatively low polarity aglycone, exhibited stronger antimicrobial activity than its corresponding glycoside 2. The results indicated that sphingolipids could be the main antimicrobial compounds in the crude methanol extract of cucumber stems. |
| 关键词 | Cucurbitaceae Cucumber (Cucumis Sativus L.) Sphingolipid Antimicrobial Activity Phytopathogenic Fungi And Bacteria |
| 学科领域 | Chemistry, Organic |
| DOI | 10.3390/molecules15129288 |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000285709000049 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kib.ac.cn/handle/151853/4878 |
| 专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.China Agr Univ, Coll Agron & Biotechnol, Beijing 100193, Peoples R China 2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China 3.China Agr Univ, Coll Anim Sci & Technol, Beijing 100193, Peoples R China |
| 推荐引用方式 GB/T 7714 | Tang, Jing,Meng, Xiangjie,Liu, Hao,et al. Antimicrobial Activity of Sphingolipids Isolated from the Stems of Cucumber (Cucumis sativus L.)[J]. MOLECULES,2010,15(12):9288-9297. |
| APA | Tang, Jing.,Meng, Xiangjie.,Liu, Hao.,Zhao, Jianglin.,Zhou, Ligang.,...&Yang, Fuyu.(2010).Antimicrobial Activity of Sphingolipids Isolated from the Stems of Cucumber (Cucumis sativus L.).MOLECULES,15(12),9288-9297. |
| MLA | Tang, Jing,et al."Antimicrobial Activity of Sphingolipids Isolated from the Stems of Cucumber (Cucumis sativus L.)".MOLECULES 15.12(2010):9288-9297. |
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