Antimicrobial Activity of Sphingolipids Isolated from the Stems of Cucumber (Cucumis sativus L.)

doi:10.3390/molecules15129288

	Antimicrobial Activity of Sphingolipids Isolated from the Stems of Cucumber (Cucumis sativus L.)
	Tang, Jing 1,2; Meng, Xiangjie 1; Liu, Hao 1; Zhao, Jianglin 1; Zhou, Ligang 1; Qiu, Minghua2 ; Zhang, Xianming 2; Yu, Zhu 3; Yang, Fuyu 3
	2010-12-01
发表期刊	MOLECULES
ISSN	1420-3049
卷号	15 期号:12 页码:9288-9297
摘要	Three antimicrobial sphingolipids were separated by bioassay-guided isolation from the chloroform fraction of the crude methanol extract of cucumber (Cucumis sativus L.) stems and identified as (2S,3S,4R,10E)-2-[(2'R)-2-hydroxytetra-cosanoylamino]-1,3,4-octadecanetriol-10-ene (1), 1-O-beta-D-glucopyranosyl(2S,3S,4R,10E)-2-[(2'R)-2-hydroxytetracosanoylamino]-1,3,4-octadecanetriol-10-ene (2) and soya-cerebroside I (3) by their physicochemical properties and spectroscopic analysis. They were evaluated to show antifungal and antibacterial activity on test microorganisms including four fungal and three bacterial species. Among them, compound 1, a relatively low polarity aglycone, exhibited stronger antimicrobial activity than its corresponding glycoside 2. The results indicated that sphingolipids could be the main antimicrobial compounds in the crude methanol extract of cucumber stems.
关键词	Cucurbitaceae Cucumber (Cucumis Sativus L.) Sphingolipid Antimicrobial Activity Phytopathogenic Fungi And Bacteria
学科领域	Chemistry, Organic
DOI	10.3390/molecules15129288
收录类别	SCI
语种	英语
WOS记录号	WOS:000285709000049
引用统计	被引频次：23[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/4878
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.China Agr Univ, Coll Agron & Biotechnol, Beijing 100193, Peoples R China 2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China 3.China Agr Univ, Coll Anim Sci & Technol, Beijing 100193, Peoples R China
推荐引用方式 GB/T 7714	Tang, Jing,Meng, Xiangjie,Liu, Hao,et al. Antimicrobial Activity of Sphingolipids Isolated from the Stems of Cucumber (Cucumis sativus L.)[J]. MOLECULES,2010,15(12):9288-9297.
APA	Tang, Jing.,Meng, Xiangjie.,Liu, Hao.,Zhao, Jianglin.,Zhou, Ligang.,...&Yang, Fuyu.(2010).Antimicrobial Activity of Sphingolipids Isolated from the Stems of Cucumber (Cucumis sativus L.).MOLECULES,15(12),9288-9297.
MLA	Tang, Jing,et al."Antimicrobial Activity of Sphingolipids Isolated from the Stems of Cucumber (Cucumis sativus L.)".MOLECULES 15.12(2010):9288-9297.

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