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题名: Antimicrobial Activity of Sphingolipids Isolated from the Stems of Cucumber (Cucumis sativus L.)
作者: Tang, Jing1, 2; Meng, Xiangjie1; Liu, Hao1; Zhao, Jianglin1; Zhou, Ligang1; null(邱明华)2; Zhang, Xianming2; Yu, Zhu3; Yang, Fuyu3
刊名: MOLECULES
关键词: Cucurbitaceae ; cucumber (Cucumis sativus L.) ; sphingolipid ; antimicrobial activity ; phytopathogenic fungi and bacteria
英文摘要: Three antimicrobial sphingolipids were separated by bioassay-guided isolation from the chloroform fraction of the crude methanol extract of cucumber (Cucumis sativus L.) stems and identified as (2S,3S,4R,10E)-2-[(2'R)-2-hydroxytetra-cosanoylamino]-1,3,4-octadecanetriol-10-ene (1), 1-O-beta-D-glucopyranosyl(2S,3S,4R,10E)-2-[(2'R)-2-hydroxytetracosanoylamino]-1,3,4-octadecanetriol-10-ene (2) and soya-cerebroside I (3) by their physicochemical properties and spectroscopic analysis. They were evaluated to show antifungal and antibacterial activity on test microorganisms including four fungal and three bacterial species. Among them, compound 1, a relatively low polarity aglycone, exhibited stronger antimicrobial activity than its corresponding glycoside 2. The results indicated that sphingolipids could be the main antimicrobial compounds in the crude methanol extract of cucumber stems.
出版日期: 2010-12-01
卷号: 15, 期号:12, 页码:9288-9297
DOI标识: 10.3390/molecules15129288
语种: 英语
ISSN号: 1420-3049
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/4878
Appears in Collections:植物化学与西部植物资源持续利用国家重点实验室_期刊论文

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作者单位: 1.China Agr Univ, Coll Agron & Biotechnol, Beijing 100193, Peoples R China
2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China
3.China Agr Univ, Coll Anim Sci & Technol, Beijing 100193, Peoples R China

Recommended Citation:
Tang, J; Meng, XJ; Liu, H; Zhao, JL; Zhou, LG; Qiu, MH; Zhang, XM; Yu, Z; Yang, FY.Antimicrobial Activity of Sphingolipids Isolated from the Stems of Cucumber (Cucumis sativus L.),MOLECULES,2010,15(12):9288-9297
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