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题名: Antioxidant Lignans from the Fruits of Broussonetia papyrifera
作者: Mei, Ren-Qiang1, 2; Wang, Yue-Hu1; Du, Guan-Hua3; Liu, Guang-Ming4; Zhang, Li1, 3; null(程永现)1
刊名: JOURNAL OF NATURAL PRODUCTS
关键词: CONSTITUENTS ; FLAVONOIDS
英文摘要: Nine new lignans, chushizisins A-I (1-9), and three known lignans, threo-1-(4-hydroxy-3-methoxyphenyl)-2-{4-[(E)-3-hydroxy-1-propenyl]-2-methoxyphenoxy}-1,3-propanediol (10), erythro-1-(4-hydroxy-3-methoxyphenyl)-2-{4-[(E)-3-hydroxy-1-propenyl]-2-methoxyphenoxy}-1,3-propanediol (11), and 3-[2-(4- hydroxyphenyl)-3-hydroxymethyl-2,3-dihydro-1-benzofuran-5-yl]propan-1-ol (12), were isolated from the fruits of Broussonetia papyrifera. Their structures were elucidated using spectroscopic methods. Compounds 1, 5, 6, 8, 9, and 11 exhibited antioxidant activities against H(2)O(2)-induced impairment in PC12 cells, while compounds 1, 2, 4, 7, and 11 showed DPPH radical-scavenging activities with IC(50) values of 236.8, 156.3, 273.9, 281.1, and 60.9 mu M, respectively.
出版日期: 2009-04-01
卷号: 72, 期号:4, 页码:621-625
DOI标识: 10.1021/np800488p
语种: 英语
收录类别: SCI ; IC
学科分类: Plant Sciences; Chemistry, Medicinal; Pharmacology & Pharmacy
ISSN号: 0163-3864
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/4804
Appears in Collections:植物化学与西部植物资源持续利用国家重点实验室_期刊论文

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作者单位: 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China
3.Chinese Acad Med Sci, Inst Mat Med, Beijing 100050, Peoples R China
4.Dali Univ, Coll Pharmaceut Sci, Dali 671002, Yunnan, Peoples R China

Recommended Citation:
Mei, RQ; Wang, YH; Du, GH; Liu, GM; Zhang, L; Cheng, YX.Antioxidant Lignans from the Fruits of Broussonetia papyrifera,JOURNAL OF NATURAL PRODUCTS,2009,72(4):621-625
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