Antioxidant Lignans from the Fruits of Broussonetia papyrifera
Mei, Ren-Qiang1,2; Wang, Yue-Hu1; Du, Guan-Hua3; Liu, Guang-Ming4; Zhang, Li1,3; Cheng, Yong-Xian1
2009-04-01
Source PublicationJOURNAL OF NATURAL PRODUCTS
ISSN0163-3864
Volume72Issue:4Pages:621-625
AbstractNine new lignans, chushizisins A-I (1-9), and three known lignans, threo-1-(4-hydroxy-3-methoxyphenyl)-2-{4-[(E)-3-hydroxy-1-propenyl]-2-methoxyphenoxy}-1,3-propanediol (10), erythro-1-(4-hydroxy-3-methoxyphenyl)-2-{4-[(E)-3-hydroxy-1-propenyl]-2-methoxyphenoxy}-1,3-propanediol (11), and 3-[2-(4- hydroxyphenyl)-3-hydroxymethyl-2,3-dihydro-1-benzofuran-5-yl]propan-1-ol (12), were isolated from the fruits of Broussonetia papyrifera. Their structures were elucidated using spectroscopic methods. Compounds 1, 5, 6, 8, 9, and 11 exhibited antioxidant activities against H(2)O(2)-induced impairment in PC12 cells, while compounds 1, 2, 4, 7, and 11 showed DPPH radical-scavenging activities with IC(50) values of 236.8, 156.3, 273.9, 281.1, and 60.9 mu M, respectively.
KeywordConstituents Flavonoids
Subject AreaPlant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
DOI10.1021/np800488p
Indexed BySCI ; IC
Language英语
WOS Research AreaPlant Sciences ; Pharmacology & Pharmacy
WOS SubjectPlant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
WOS IDWOS:000265530000004
Citation statistics
Cited Times:37[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/4804
Collection植物化学与西部植物资源持续利用国家重点实验室
Affiliation1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China
3.Chinese Acad Med Sci, Inst Mat Med, Beijing 100050, Peoples R China
4.Dali Univ, Coll Pharmaceut Sci, Dali 671002, Yunnan, Peoples R China
Recommended Citation
GB/T 7714
Mei, Ren-Qiang,Wang, Yue-Hu,Du, Guan-Hua,et al. Antioxidant Lignans from the Fruits of Broussonetia papyrifera[J]. JOURNAL OF NATURAL PRODUCTS,2009,72(4):621-625.
APA Mei, Ren-Qiang,Wang, Yue-Hu,Du, Guan-Hua,Liu, Guang-Ming,Zhang, Li,&Cheng, Yong-Xian.(2009).Antioxidant Lignans from the Fruits of Broussonetia papyrifera.JOURNAL OF NATURAL PRODUCTS,72(4),621-625.
MLA Mei, Ren-Qiang,et al."Antioxidant Lignans from the Fruits of Broussonetia papyrifera".JOURNAL OF NATURAL PRODUCTS 72.4(2009):621-625.
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