Tetranortriterpenoids from the Leaves of Cipadessa cinerascens | |
Fang, Xin1,2; Di, Ying-Tong1; Li, Chun-Shun1; Geng, Zhao-Liang1; Zhang, Zhen1; Zhang, Yu1; Lu, Yang3; Zheng, Qi-Tai3; Yang, Shi-Yin3; Hao, Xiao-Jiang1 | |
2009-04-01 | |
发表期刊 | JOURNAL OF NATURAL PRODUCTS |
ISSN | 0163-3864 |
卷号 | 72期号:4页码:714-718 |
摘要 | Seven known and six new tetranortriterpenoids, cineracipadesins A-F (1-6), were isolated from the leaves of Cipadessa cinerascens. Compound 1 has a mexicanolide-type structural skeleton with a rare 9 alpha, 11 alpha-epoxide ring; compound 2 has a methyl angolensate-type structure with 9,11-dihydroxy groups, representing the first example of a precursor of a trijugin-type limonoid; and 3 is the first reported methyl angolensate-type limonoid with a ketone group at ring C. Their structures were determined with extensive spectroscopic analysis. X-ray crystallography confirmed the structure of 1. The ability of compounds 1-7 to inhibit the growth of the P-388 murine leukemia cell line was evaluated. |
关键词 | Absolute Stereochemistry Venenata Rbr Leaves 19-epiajmalicine Raucaffrinoline Proliferation Lochnericine Scholaris Plants |
学科领域 | Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy |
DOI | 10.1021/np800656r |
收录类别 | SCI ; IC |
语种 | 英语 |
WOS记录号 | WOS:000265530000021 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.kib.ac.cn/handle/151853/4792 |
专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China 3.Chinese Acad Sci, Inst Mat Med, Beijing 100050, Peoples R China |
推荐引用方式 GB/T 7714 | Fang, Xin,Di, Ying-Tong,Li, Chun-Shun,et al. Tetranortriterpenoids from the Leaves of Cipadessa cinerascens[J]. JOURNAL OF NATURAL PRODUCTS,2009,72(4):714-718. |
APA | Fang, Xin.,Di, Ying-Tong.,Li, Chun-Shun.,Geng, Zhao-Liang.,Zhang, Zhen.,...&Hao, Xiao-Jiang.(2009).Tetranortriterpenoids from the Leaves of Cipadessa cinerascens.JOURNAL OF NATURAL PRODUCTS,72(4),714-718. |
MLA | Fang, Xin,et al."Tetranortriterpenoids from the Leaves of Cipadessa cinerascens".JOURNAL OF NATURAL PRODUCTS 72.4(2009):714-718. |
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