Tetranortriterpenoids from the Leaves of Cipadessa cinerascens
Fang, Xin1,2; Di, Ying-Tong1; Li, Chun-Shun1; Geng, Zhao-Liang1; Zhang, Zhen1; Zhang, Yu1; Lu, Yang3; Zheng, Qi-Tai3; Yang, Shi-Yin3; Hao, Xiao-Jiang1
2009-04-01
发表期刊JOURNAL OF NATURAL PRODUCTS
ISSN0163-3864
卷号72期号:4页码:714-718
摘要Seven known and six new tetranortriterpenoids, cineracipadesins A-F (1-6), were isolated from the leaves of Cipadessa cinerascens. Compound 1 has a mexicanolide-type structural skeleton with a rare 9 alpha, 11 alpha-epoxide ring; compound 2 has a methyl angolensate-type structure with 9,11-dihydroxy groups, representing the first example of a precursor of a trijugin-type limonoid; and 3 is the first reported methyl angolensate-type limonoid with a ketone group at ring C. Their structures were determined with extensive spectroscopic analysis. X-ray crystallography confirmed the structure of 1. The ability of compounds 1-7 to inhibit the growth of the P-388 murine leukemia cell line was evaluated.
关键词Absolute Stereochemistry Venenata Rbr Leaves 19-epiajmalicine Raucaffrinoline Proliferation Lochnericine Scholaris Plants
资助信息Ministry of Science and Technology [2009CB940900, 2009CB522303]
收录类别SCI ; IC
语种英语
引用统计
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/4792
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
3.Chinese Acad Sci, Inst Mat Med, Beijing 100050, Peoples R China
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Fang, Xin,Di, Ying-Tong,Li, Chun-Shun,et al. Tetranortriterpenoids from the Leaves of Cipadessa cinerascens[J]. JOURNAL OF NATURAL PRODUCTS,2009,72(4):714-718.
APA Fang, Xin.,Di, Ying-Tong.,Li, Chun-Shun.,Geng, Zhao-Liang.,Zhang, Zhen.,...&Hao, Xiao-Jiang.(2009).Tetranortriterpenoids from the Leaves of Cipadessa cinerascens.JOURNAL OF NATURAL PRODUCTS,72(4),714-718.
MLA Fang, Xin,et al."Tetranortriterpenoids from the Leaves of Cipadessa cinerascens".JOURNAL OF NATURAL PRODUCTS 72.4(2009):714-718.
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