| (+)-N-deoxymillitarinone A, a neuritogenic pyridone alkaloid from the insect pathogenic fungus Paecilomyces farinosus | |
| Cheng, YX ; Schneider, B ; Riese, U ; Schubert, B ; Li, ZZ ; Hamburger, M | |
| 通讯作者 | Hamburger, M, Kunming Inst Bot, CAS, Longquan Rd 610, Kunming 650204, Peoples R China |
| 2006 | |
| 发表期刊 | JOURNAL OF NATURAL PRODUCTS
 |
| ISSN | 0163-3864 |
| 卷号 | 69期号:3页码:436-438 |
| 摘要 | A new pyridone alkaloid, (+)-N-deoxymilitarinone A (1), was isolated from Paecilomyces farinosus RCEF 0097 along with the related metabolites, militarinone D and militarinone B. The sterol 22E,4R-ergosta-7,22-diene-3 beta,5 alpha,6 beta,9 alpha-tetraol was also identified. The structures were established by spectroscopic methods, in particular with the aid of extensive NMR experiments. Compound 1 induced neurite sprouting in PC 12 cells when tested at 33 and 100 mu M concentrations. A cytotoxic effect was observed in human neurons (IMR-32) at a concentration of 100 mu M. |
| 关键词 | Tripterygium Hypoglaucum Demethylzeylasteral Hepatitis c Virus Rna-dependent Rna Polymerase Yunnan Crude Drugs |
| 学科领域 | Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy |
| 收录类别 | SCI |
| 语种 | English |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kib.ac.cn/handle/151853/4758 |
| 专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Cheng, YX,Schneider, B,Riese, U,et al. (+)-N-deoxymillitarinone A, a neuritogenic pyridone alkaloid from the insect pathogenic fungus Paecilomyces farinosus[J]. JOURNAL OF NATURAL PRODUCTS,2006,69(3):436-438. |
| APA | Cheng, YX,Schneider, B,Riese, U,Schubert, B,Li, ZZ,&Hamburger, M.(2006).(+)-N-deoxymillitarinone A, a neuritogenic pyridone alkaloid from the insect pathogenic fungus Paecilomyces farinosus.JOURNAL OF NATURAL PRODUCTS,69(3),436-438. |
| MLA | Cheng, YX,et al."(+)-N-deoxymillitarinone A, a neuritogenic pyridone alkaloid from the insect pathogenic fungus Paecilomyces farinosus".JOURNAL OF NATURAL PRODUCTS 69.3(2006):436-438. |
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