(+)-N-deoxymillitarinone A, a neuritogenic pyridone alkaloid from the insect pathogenic fungus Paecilomyces farinosus
Cheng, YX ; Schneider, B ; Riese, U ; Schubert, B ; Li, ZZ ; Hamburger, M
2006
发表期刊JOURNAL OF NATURAL PRODUCTS
ISSN0163-3864
卷号69期号:3页码:436-438
摘要A new pyridone alkaloid, (+)-N-deoxymilitarinone A (1), was isolated from Paecilomyces farinosus RCEF 0097 along with the related metabolites, militarinone D and militarinone B. The sterol 22E,4R-ergosta-7,22-diene-3 beta,5 alpha,6 beta,9 alpha-tetraol was also identified. The structures were established by spectroscopic methods, in particular with the aid of extensive NMR experiments. Compound 1 induced neurite sprouting in PC 12 cells when tested at 33 and 100 mu M concentrations. A cytotoxic effect was observed in human neurons (IMR-32) at a concentration of 100 mu M.
关键词Tripterygium Hypoglaucum Demethylzeylasteral Hepatitis c Virus Rna-dependent Rna Polymerase Yunnan Crude Drugs
收录类别SCI
语种英语
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/4758
专题植物化学与西部植物资源持续利用国家重点实验室
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Cheng, YX,Schneider, B,Riese, U,et al. (+)-N-deoxymillitarinone A, a neuritogenic pyridone alkaloid from the insect pathogenic fungus Paecilomyces farinosus[J]. JOURNAL OF NATURAL PRODUCTS,2006,69(3):436-438.
APA Cheng, YX,Schneider, B,Riese, U,Schubert, B,Li, ZZ,&Hamburger, M.(2006).(+)-N-deoxymillitarinone A, a neuritogenic pyridone alkaloid from the insect pathogenic fungus Paecilomyces farinosus.JOURNAL OF NATURAL PRODUCTS,69(3),436-438.
MLA Cheng, YX,et al."(+)-N-deoxymillitarinone A, a neuritogenic pyridone alkaloid from the insect pathogenic fungus Paecilomyces farinosus".JOURNAL OF NATURAL PRODUCTS 69.3(2006):436-438.
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