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题名: Nematicidal epipolysulfanyldioxopiperazines from Gliocladium roseum
作者: Dong, JY; He, HP; Shen, YM; Zhang, KQ
刊名: JOURNAL OF NATURAL PRODUCTS
关键词: STREPTOCARPUS-DUNNII
英文摘要: Five new verticillin-type epipolysulfanyldioxopiperazines, gliocladine A (1), B (2), C (3), D (4), and E (5), were isolated from wheat solid-substrate fermentation of Gliocladium roseum 1A, along with four known compounds, verticillin A (6), 11'-deoxyverticillin A (7), Sch52900 (8), and Sch52901 (9). Their structures were elucidated by extensive 1D and 2D NMR studies, MS, and chemical transformations. In vitro immersion tests showed that all nine compounds exhibited antinematodal activity against Caenorhabditis elegans and Panagrellus redivivus. The monomeric epipolysulfanydioxopiperazines (3-5), with the indole moiety, were found to be less active than the dimeric compounds (1, 2, 6-8).
出版日期: 2005-10-01
卷号: 68, 期号:10, 页码:1510-1513
DOI标识: 10.1021/np0502241
语种: 英语
收录类别: SCI ; IC ; CCR
学科分类: Plant Sciences; Chemistry, Medicinal; Pharmacology & Pharmacy
ISSN号: 0163-3864
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/4726
Appears in Collections:植物化学与西部植物资源持续利用国家重点实验室_期刊论文

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作者单位: 1.Yunnan Univ, Key Lab Conservat & Utilizat Bioresourses, Kunming 650091, Yunnan, Peoples R China
2.Chinese Acad Sci, Kunming Inst Bot, Lab Phytochem, Kunming 650204, Yunnan, Peoples R China

Recommended Citation:
Dong, JY; He, HP; Shen, YM; Zhang, KQ.Nematicidal epipolysulfanyldioxopiperazines from Gliocladium roseum,JOURNAL OF NATURAL PRODUCTS,2005,68(10):1510-1513
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